What to do if A + B doesn't work |
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| Affiliation: | 1. Newborn Services, Middlemore Hospital, Otahuhu, Auckland, New Zealand;2. Division of Neonatology, Center for Maternal Fetal Neonatal and Reproductive Medicine, National Center for Child Health and Development, Tokyo, Japan;1. University of Texas;2. James Cook University Hospital;1. Neonatal Unit, University Hospitals of Leicester NHS Trust, Leicester, UK;2. Department of Health Sciences, University of Leicester, Leicester, UK;1. Division of Nephrology, Children’s National Hospital, Washington District of Columbia, USA;2. Division of Infectious Diseases, Children’s National Hospital, Washington District of Columbia, USA;3. Department of Pediatrics, George Washington University School of Medicine, Washington, District of Columbia, USA;4. Elizabeth Glaser Pediatrics AIDS Foundation, Washington, District of Columbia, USA;5. Child Health Research Center, Department of Pediatrics, University of Virginia, School of Medicine, Charlottesville, Virginia, USA;1. Department of Neurology, Washington University, St. Louis, Missouri;2. Department of Pediatrics, Washington University, St. Louis, Missouri;3. Department of Radiology, Washington University, St. Louis, Missouri;4. Department of Paediatrics, The Hospital for Sick Children and University of Toronto, Ontario, Canada;5. Department of Neurology, Children''s National Health System, Washington, DC;6. Department of Neurology, Boston Children''s Hospital and Harvard Medical School, Boston, Massachusetts;7. Department of Neurology, Benioff Children''s Hospital, University of California, San Francisco, California;8. Department of Pediatrics, Benioff Children''s Hospital, University of California, San Francisco, California;9. Department of Epidemiology and Biostatistics, Benioff Children''s Hospital, University of California, San Francisco, California;1. University of Warwick, Warwick Medical School, Coventry, CV4 7AL, UK;2. Anaesthesia and Intensive Care Medicine, Royal United Hospital, Bath, BA1 3NG, UK;3. Department of Emergency Medicine, Virginia Commonwealth University Health, Richmond, VA, USA;4. Intensive Care, Liverpool and Macquarie University Hospitals, University of New South Wales and Macquarie University, Sydney, Australia;5. Critical Care Medicine, University of Warwick, Warwick Medical School and University Hospitals Birmingham NHS Foundation Trust, Coventry, CV4 7AL, UK;6. Anaesthesia and Intensive Care Medicine, Southmead Hospital, North Bristol NHS Trust, Bristol, BS10 5NB, UK |
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| Abstract: | ![]()
The majority of newborn resuscitations require very little beyond simple airway management and assisted ventilation. If cardiovascular collapse is serious enough to warrant additional support, resuscitation algorithms recommend moving to chest compressions and then on to medications and possibly volume replacement if vital signs remain marginal or absent. The evidence base upon which this part of the neonatal resuscitation algorithm is structured is sparse. Chest compressions and medications are rare interventions that do not lend themselves easily to clinical trials. Slowly but surely, however, the genesis of an empirical evidence base for this part of the algorithm is beginning to appear. |
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| Keywords: | Resuscitation Newborn Asphyxia Chest compressions Adrenaline Volume expansion |
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