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Viral infections of the gastrointestinal tract
Affiliation:1. Clinical Pharmacology Unit, Instituto de Medicina Molecular, Lisbon, Portugal;2. Laboratory of Clinical Pharmacology, Faculty of Medicine, University of Lisbon, Portugal;3. Cardiology Department, Hospital Garcia de Orta, Almada, Portugal;4. Cardiology Department, CCUL, CAML, Faculty of Medicine, Lisbon, Portugal;5. Portuguese Collaborating Centre of the Cochrane Iberoamerican Network, Faculty of Medicine, University of Lisbon, Portugal;6. Evidence Based Medicine Centre, Faculty of Medicine, University of Lisbon, Portugal
Abstract:Infectious agents are one of the potential etiologies for the pathologic findings of the gastrointestinal (GI) specimens. Various clinical settings such as general debilitation, infancy or advanced age, immunocompromised state, hematologic malignancies, chemotherapy or diabetes predispose patients to viral infections of the GI tract. Endoscopic evaluation with biopsies are often performed as part of the diagnostic workup of such patients. Considering the site and the pattern of injury along with microscopic recognition of the viral inclusions are essential in identifying the possible cause of injury. The aim of this article is to review the most commonly encountered viral infections of the GI tract in order to provide some guidance in differentiating between the various responsible viral agents and to highlight some of the challenges faced by pathologists in approaching such cases in daily practice.
Keywords:gastrointestinal tract  review  viral infections
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