Variability of neonatal hyperbilirubinemia of non-immune cause in the clinical practice |
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| Affiliation: | 1. General University Hospital of Elche, C/Ernesto Martínez 2, 8° Puerta 1, 03203, Elche, Alicante, Spain;2. General University Hospital of Elche, C/Federico García Lorca 25, 1°, 03204, Elche, Alicante, Spain;3. Professor of Nursing Management Services, Health Sciences Faculty of University of Alicante, Carretera San Vicente s/n, 03690 Spain;1. The Townsville Hospital, Australia;2. James Cook University, Australia;3. Cerebral Palsy Alliance, Australia;1. Advanced Neonatal Nurse Practitioner, NHS Tayside, UK;2. Advanced Neonatal Practice Program, Edinburgh Napier University, UK;3. Lecturer in Neonatal Nursing Studies, Edinburgh Napier University, UK;4. Professor in Maternal Health, Edinburgh Napier University, UK;1. Department of Regenerative Medicine and Pediatrics, G.R. Doshi and K.M. Mehta Institute of Kidney Diseases & Research Centre (IKDRC) - Dr. H.L. Trivedi Institute of Transplantation Sciences (ITS), India;2. Department of Pathology, Laboratory Medicine, Transfusion Services and Immunohematology, G.R. Doshi and K.M. Mehta Institute of Kidney Diseases & Research Centre (IKDRC) - Dr. H.L. Trivedi Institute of Transplantation Sciences (ITS), India;3. Department of Obstetrics and Gynecology, G.R. Doshi and K.M. Mehta Institute of Kidney Diseases & Research Centre (IKDRC) - Dr. H.L. Trivedi Institute of Transplantation Sciences (ITS), India;4. Department of Anesthesiology and Critical Care, G.R. Doshi and K.M. Mehta Institute of Kidney Diseases & Research Centre (IKDRC) - Dr. H.L. Trivedi Institute of Transplantation Sciences (ITS), India;5. Department of Nephrology and Transplantation Sciences, G.R. Doshi and K.M. Mehta Institute of Kidney Diseases & Research Centre (IKDRC) - Dr. H.L. Trivedi Institute of Transplantation Sciences (ITS), India |
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| Abstract: | ObjectiveTo know the variability in clinical practice related to the treatment of neonatal hyperbilirubinemia in the Neonatology Unit of the General University Hospital of Elche (Spain), where a specific clinical practice guide is not used.MethodRetrospective audit of medical records of 130 patients ≥35 weeks of gestational age who presented neonatal indirect (unconjugated) hyperbilirubinemia of non-immune cause during their first weeks of life, and required treatment with phototherapy in the Neonatal Unit of the General University Hospital of Elche, during the period 2010–2014.ResultTotal serum bilirubin (TSB) levels at admission, the phototherapy time and the clinical stay vary with the type of applied phototherapy (p < 0,01), management of phototherapy (p < 0,01), and increase in TSB (p < 0,02).Phototherapy time is associated with TSB levels control by blood analysis sent to the laboratory (p < 0,05) and capillary radiometer (p < 0,03), total stools (p < 0,01), and clinical stay (p < 0,01).TSB levels at admission changes with neonatal age (p < 0,01), provenance (p < 0,01), and lactation during hospitalization (p < 0,03).In addition, the clinical stay is associated with the TSB levels control by capillary radiometer (p < 0,01), and total stools (p < 0,01).ConclusionsThe results obtained show variability related to the TSB level at admission, the distribution of phototherapy time, and the clinical stay. |
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| Keywords: | Phototherapy Neonatal hyperbilirubinemia Neonatal jaundice Variability |
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