| A Study of Hemorrheologic Changes in Patients with Severe Viral Hepatitis |
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| 作者姓名： | 王宇明 向居正 李贤玉 胡仕琦 |
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| 作者单位： | Department of Infectious Diseases First Teaching Hospital，Third Military Medical College，Chongqing，Department of Infectious Diseases，First Teaching Hospital，Third Military Medical College，Chongqing，Department of Infectious Diseases，First Teaching Hospital，Third Military Medical College，Chongqing，Department of Infectious Diseases，First Teaching Hospital，Third Military Medical College，Chongqing |
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| 摘 要： | The study of the micro and macro-hemorrheologic changes and theflow conditions of the nail-fold microcirculation in 30 patients with severe viralhepatitis was reported.Normal individuals,and patients with acute icterichepatitis or chronic active hepatitis were employed as the controls.The changes observed in the patients with severe viral hepatitis were asfollows:The reduced viscosity of the whole blood and the plasma viscosityincreased markedly;the dispersion rate of the values of blood viscosity increasedas the clinical state of the patient became worse;and the factors increasing theblood viscosity(i.e.increase of the immuno-globulin level,prolongation of theerythrocyte electrophoretic mobility time,and increase of RBC sedimentation rate)and those decreasing the blood viscosity(i.e.decrease of hematocrit reading,fibrinogen level and platelet aggregation ratio)existed simultaneously in thepatient.The changes of the flow conditions of the nail-fold microcirculation werein close correlation with the increase of blood viscosity and the severity of thedisease.The etiology and mechanism of the above mentioned changes were discussed
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A Study of Hemorrheologic Changes in Patients with Severe Viral Hepatitis |
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| Wang Yuming Xiang Juzheng Li Xianyu Hu Shiqi.A Study of Hemorrheologic Changes in Patients with Severe Viral Hepatitis[J].Journal of Medical Colleges of PLA(China),1987(1). |
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| Authors: | Wang Yuming Xiang Juzheng Li Xianyu Hu Shiqi |
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| Institution: | Wang Yuming Xiang Juzheng Li Xianyu Hu Shiqi Department of Infectious Diseases,First Teaching Hospital,Third Military Medical College,Chongqing |
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| Abstract: | The study of the micro and macro-hemorrheologic changes and the flow conditions of the nail-fold microcirculation in 30 patients with severe viral hepatitis was reported.Normal individuals,and patients with acute icteric hepatitis or chronic active hepatitis were employed as the controls. The changes observed in the patients with severe viral hepatitis were as follows:The reduced viscosity of the whole blood and the plasma viscosity increased markedly;the dispersion rate of the values of blood viscosity increased as the clinical state of the patient became worse;and the factors increasing the blood viscosity(i.e.increase of the immuno-globulin level,prolongation of the erythrocyte electrophoretic mobility time,and increase of RBC sedimentation rate) and those decreasing the blood viscosity(i.e.decrease of hematocrit reading, fibrinogen level and platelet aggregation ratio)existed simultaneously in the patient.The changes of the flow conditions of the nail-fold microcirculation were in close correlation with the increase of blood viscosity and the severity of the disease. The etiology and mechanism of the above mentioned changes were discussed |
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| Keywords: | severe viral hepatitis blood viscosity microcirculation |
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