大学生肺炎支原体感染84 例临床分析

目的分析大学生肺炎支原体感染的临床特点及治疗经验。方法对我院2009年6月-2013年5月肺炎支原体感染病例的临床资料进行回顾性分析、总结。结果表现为上呼吸道感染58例（69％），急性支气管炎22例（26．2％），肺楚4例（4．8％）；肺外表现9例（（10．7％），其中，皮疹3例（3．6％）、消化系统症状4例（4.8％）、关节痛2例（2．4％）。全部首选大环内酯类药物治疗，效果不佳或副作用较大时改用喹诺酮类，合并细菌感染时联用头孢菌素。结论大学生肺炎支原体感染以刺激性咳嗽为主，干咳或伴少量白痰，症状相对较轻，可出现肺外表现，外周血白细胞计数多正常，肺炎支原体抗体检测有诊断意义；大环内酯类疗效显著，合并细菌感染时可联合应用β-内酰胺类。

Clinical analysis of 84 college students infected with mycoplasma pneumoniae

Objective To explore and summarize the clinic characteristics and treatment experiences of mycoplasma pneumoniae infection in college students. Methods The clinical information of mycoplasma pneumoniae infection cases was retrospective analyzed in marine police academy from June, 2009 to May, 2013. Results There were 58 upper respiratory tract infection cases （69 % ）, 22 acute bronchitis cases （26.2 % ）, 4 pneumonia cases （4.8 % ） and 9 extrapulmonary manifestations cases （10.7%）, of which there were 3 tetter cases （3.6%）, 4 digestive system syndromes cases （ 4.8 % ） and 2 arthralgia cases （2.4 % ）. Macrolides were preferred to treat all the cases. When the effects were poor or resulted in major side effects, the treatment was switched to 4-quinolones which were combined with cephalosporin to handle the cases with incidental bacteria infection. Conclusions Mycoplasma pneumoniae infection in college students is represented as irritable cough, hacking cough or small amounts of incidental white phlegm. The symptoms are relatively mild and likely displayed as extrapulmonary manifestations. The peripheral white blood cell counts are mostly normal. The mycoplasma pneumoniae antibody tests are clinically significant. Macrolides are greatly effective, and when combined with β-lactams, they are effective in the cases of incidental bacteria infection.