42例狼疮性肾炎的病理与临床分析

目的探讨狼疮性肾炎（LN）的病理与临床特点,了解病理改变与临床表现之间的联系。方法回顾性分析42例LN患者的病理类型与临床特征。结果Ⅰ、Ⅱ、Ⅲ、Ⅳ、Ⅴ型各占2.3%、11.9%、28.5%、42.6%、14.3%;结论狼疮性肾炎的病理类型与临床表现、实验室检查有一定联系;肾活检对判断疾病活动性,指导治疗与估计预后有重要意义。

Clinical and pathological analysis of 42 cases with lupus nephritis

Objective To analyze the pathological category and the clinical characteristics of Lupus nephritisretrospectively. Method The pathological category and clinical characteristics of lupus nephritis. Result Among41 cases, all patients were sufered from activitive kidney involvement：with type Ⅰ,Ⅱ, Ⅲ,Ⅳ Vaccountingfor 2. 3%, 11.9% ,28.5% ,42. 6% and 14. 3%. Conclusion There is a relation between LN pathologicalchang and LN clinical manifestation and laboratory examination. Renal biopsy is important in eliagnos is of active status,in designing of therapeuticregim en and predicting of prognos is in lupus nephritis.