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| MVP与HVP方案治疗晚期NSCLC前瞻随机研究 | |
| 引用本文： | 高建飞,杜光祖,章必成,张新华,王军,朱宇泽,欧武陵. MVP与HVP方案治疗晚期NSCLC前瞻随机研究[J]. 肿瘤防治研究, 2004, 31(9): 579-580 |
| 作者姓名： | 高建飞 杜光祖 章必成 张新华 王军 朱宇泽 欧武陵 |
| 作者单位： | 430070,广州军区武汉总医院肿瘤血液科 |
| 摘 要： | 目的 比较MVP(MMC +VDS +DDP)与HVP(HCPT +VDS +DDP)方案治疗晚期非小细胞肺癌 (NSCLC)的近期、远期疗效和不良反应。方法 将 88例NSCLC随机分为MVP组和HVP组 ,分别给予MVP和HVP方案化疗 3～ 5周期 ,按WHO标准评定疗效和不良反应。结果 两组有效率 (CR +PR)分别为 36 %和 2 6 % ,二组间疗效差异无显著性意义 (P >0 .0 5 )。二组中位缓解期、中位生存期、1年生存率和 2年生存率相似。二组主要毒副反应有骨髓抑制和消化道反应 ,二组毒副反应相似。结论 MVP方案疗效稍高于HVP方案 ,所以化疗时宜选MVP方案 |
| 关 键 词： | 非小细胞肺癌 化疗 MVP方案 HVP方案 |
| 文章编号： | 1000-8578(2004)09-0579-02 |
| 收稿时间： | 2004-01-08 |
| 修稿时间： | 2004-04-07 |
A Prospective Randomized Sdudy Comparing MVP and MVP Regimens in the Treatment of Advanced Non-small Cell Lung Cancer |
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| GAO Jian-fei,DU Guang-zu,ZHANG Bi-cheng,ZHANG Xin-hua,WANG Jun,ZHU Yu-ze,OU Wu-ling. A Prospective Randomized Sdudy Comparing MVP and MVP Regimens in the Treatment of Advanced Non-small Cell Lung Cancer[J]. Cancer Research on Prevention and Treatment, 2004, 31(9): 579-580 | |
| Authors: | GAO Jian-fei DU Guang-zu ZHANG Bi-cheng ZHANG Xin-hua WANG Jun ZHU Yu-ze OU Wu-ling |
| Affiliation: | GAO Jian-fei,DU Guang-zu,ZHANG Bi-cheng,ZHANG Xin-hua,WANG Jun,ZHU Yu-ze,OU Wu-ling Department of Medical Oncology and Hematology,Wuhan General Hospital,Guangzhou Command of PLA,Wuhan 430070,China |
| Abstract: | Objective To evaluate the recent and long response and toxicity of MVP and HVP regimens in the treatment of advanced NSCLC. Methods A total of 88 cases with advanced NSCLC was randomized into two groups: MVP group (MMC+VDS+DDP), HVP group (HCPT+VDS+DDP). All patients received 3～5 cycles of chemotherapy except 4 patients. Results The response rate was 36%(15/42) in the MVP and 26%(11/42) in the HVP, no significant difference was detected between the groups (P>0.05). No significant difference was detec... |
| Keywords: | Non-Small Cell Lung Cancer(NSCLC) Chemotherapy MVP HVP |
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