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| 乙型肝炎病毒的传播与免疫耐受 | |
| 引用本文： | 李珉珉,王珊珊. 乙型肝炎病毒的传播与免疫耐受[J]. 现代预防医学, 2002, 29(6): 780-781 |
| 作者姓名： | 李珉珉 王珊珊 |
| 作者单位： | 1. 暨南大学华侨医院,510630 2. 广州军区军事医学研究所 |
| 摘 要： | 目的：探讨乙型肝炎病毒（HBV）携带者发生垂直传播的同时并未发生夫妻间水平传播的可能原因。方法：以已确定传播HBV给予代的10名女性携带者与8名男性携带者的配偶为研究对象，以1：2的原则选配对照，检测病例与对照组的IgG,IgA,IgM,C3，C4与抗-HBs。结论：研究对象未检出抗-HBs。对照组阳性率48.0%。与对照组比较女性携带者配偶IgG,C3,C4偏低，男性携带者配偶C3，C4偏低。结论：携带者配偶未发生HBV感染的原因可能是存在免疫耐受，此种免疫耐受可能与本身的免疫素质偏低有关。 |
| 关 键 词： | 乙型肝炎病毒 传播 免疫耐受 |
| 文章编号： | 1003-8507(2002)06-0780-02 |
| 修稿时间： | 2001-01-15 |
TRANSMISSION AND IMMUNOLOGICAL TOLERANCE OF HEPATITIS B VIRUS |
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| LI Min min,WANG Shan shan Huaqiao Hospital,Jinan University,Guangzhou,Guangdong .. TRANSMISSION AND IMMUNOLOGICAL TOLERANCE OF HEPATITIS B VIRUS[J]. Modern Preventive Medicine, 2002, 29(6): 780-781 | |
| Authors: | LI Min min WANG Shan shan Huaqiao Hospital Jinan University Guangzhou Guangdong . |
| Affiliation: | LI Min min,WANG Shan shan Huaqiao Hospital,Jinan University,Guangzhou,Guangdong 510630. |
| Abstract: | Objective:To study the cause by which HBV carriers transmitted HBV to their foetus,but did not transmit HBV to the spouse.Methods:The spouses of 10 female and 8 men carriers were matched with control.IgG,IgA,IgM,C3,C4 and anti HBs were detected in the groups.Results:Anti HBs of the spouses of HBV carriers was negative,while that of controls was 48 0% positive.IgG?C3?C4 of the spouses of female carriers and C3?C4 of the spouses of men carries were lower than those of the control.Conclusion:Immunological tolerance may be the cause by which the spouses of HBV carriers were not infected.The immunological tolerance was relation to immunological quality of the person. |
| Keywords: | Hepatitis B virus Transmission Immunological tolerance |
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