颈动脉粥样硬化斑块超声特征与微栓子信号的临床研究

目的:确定颈动脉粥样硬化斑块超声特征与MES的关系。材料和方法:选择急性颈内动脉系统脑梗塞患者193例,进行颈动脉彩色多普勒超声(CDI)检查,并对粥样斑块进行超声分型,进而应用TCD对存在狭窄的颈动脉远端MCA进行MES监测。结果:73.1%的患者检出颈动脉粥样硬化斑块,颈动脉狭窄的发生率为26.4%(51/193),其中48例共监测出MES(+)患者13例(27.1%),无回声/低回声斑块的病人比等回声/强回声损害的病人更易发现MES(P<0.01)。而且MES(+)病人存在较重的动脉狭窄,但差异并不显著(P>0.05)。结论:无回声/低回声斑块和MES之间可能存在一种潜在的临床关联性,提示MES可能是中风危险性增高的标志。

The clinical study of the relevance between carotid atherosclerotic plaque features on ultrasound and microembolic signal

Objective: To determine the relation of carotid atherosclerotic plaque features on ultrasound and microembolic signal(MES). Methods: Atheromatous plaque were detected in 193 patients with cerebral infarction and microembolic signals were monitored in the middle cerebral artery of carotid stenosis by transcranial Doppler. Result: Carotid atherosclerotic plaques were detected in 73.1% patients, the incidence of carotid artery stenosis was 26.4%(51/193), microembolic signals were monitored in 13 of 48 patients and MES( ) patients presented significantly increased frequency of anechogenic/hypoechogenic plaques(P<0.01). Conclusion: Probably there is latent clinical relevance between anechogenic/hypoechogenic plaques and microembolic signal, suggesting microembolic signal may be a marker of increased risk of stroke.