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Clinical Application of Exhaled Nitric Oxide Measurements in a Korean Population
Authors:Woo-Jung Song  Ji-Won Kwon  Eun-Jin Kim  Sang-Min Lee  Sae-Hoon Kim  So-Yeon Lee  Sang-Heon Kim  Heung-Woo Park  Yoon-Seok Chang  Woo Kyung Kim  Jung Yeon Shim  Ju-Hee Seo  Byoung-Ju Kim  Hyo Bin Kim  Dae Jin Song  Gwang Cheon Jang  An-Soo Jang  Jung-Won Park  Ho-Joo Yoon  Joo-Shil Lee  Sang-Heon Cho  Soo-Jong Hong
Abstract:
Nitric oxide (NO) is a biologic mediator of various physiologic functions. Recent evidence suggests the clinical utility of fractional exhaled NO (FeNO) as a biomarker for assessing asthma and other respiratory diseases. FeNO methodologies have been recently standardized by international research groups and subsequently validated in several Korean population studies. Normal ranges for FeNO have been reported for various ethnic groups, and the clinical utility has been widely evaluated in asthma and various respiratory diseases. Based on current evidence including most of Korean population data, this position paper aims to introduce the methodological considerations, and provide the guidance for the proper clinical application of FeNO measurements in Korean populations.
Keywords:Exhaled nitric oxide   reference value   guideline   position paper   asthma
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