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机械胸外按压对心脏骤停后综合征的作用观察
引用本文:李素彦,张立涛,齐惠军,刘洪英,斯重阳.机械胸外按压对心脏骤停后综合征的作用观察[J].中国医药,2014(3):322-324.
作者姓名:李素彦  张立涛  齐惠军  刘洪英  斯重阳
作者单位:河北省人民医院急诊科,石家庄050051
摘    要:目的 比较机械胸外按压与徒手胸外按压对心脏骤停后综合征的作用.方法 选择2007年1月至2013年1月河北省人民医院急诊科院内发生心跳停止,且发病前无严重基础疾病的青中年患者为研究对象,依据胸外按压方式分成徒手胸外按压的人工心肺复苏组(21例)及机械胸外按压的机械心肺复苏组(23例),记录2组患者心肺复苏后5~15 min自主循环恢复的病例数据,并记录复苏后0、24、48、72 h生化指标如肌酸激酶同工酶(CK-MB)、心肌肌钙蛋白I(cTnI)、肌酐、血尿素氮、天冬氨酸氨基转移酶/丙氨酸氨基转移酶(AST/ALT)比值及24 h、48 h 、7 d、14 d 格拉斯哥昏迷评分(GCS)、神经功能缺损评分(CSS).结果①心肺复苏后,机械心肺复苏组24、48、72 h CK-MB、cTnI均低于人工心肺复苏组CK-MB:(80.3±4.5)U/L比(98.7±8.6)U/L,(40.5±2.8)U/L比(59.4±3.0)U/L,(30.5±2.9)U/L比(38.9±3.4)U/L;cTnI:(5.0±0.5)μg/L比(6.9±0.3)μg/L,(3.8±0.7)μg/L比(4.9±0.5)μg/L,(1.9±0.5)μg/L比(2.6±0.4)μg/L],差异有统计学意义(P〈0.05); 肌酐、血尿素氮、AST/ALT在复苏后24、48 h均低于人工心肺复苏组肌酐:(179±10)μmol/L比(201±4)μmol/L,(68±7)μmol/L比(78±5)μmol/L;血尿素氮:(19.3±1.5)mmol/L比(24.9±0.9)mmol/L,(10.9±1.2)mmol/L比(14.4±2.3)mmol/L;AST/ALT:(1.3±0.2)比(1.8±0.4),(1.0±0.2)比(1.1±0.3)],差异有统计学意义(P〈0.05).②心肺复苏后,机械心肺复苏组GCS评分、CSS评分在24、48、72 h及7、14 d均优于人工心肺复苏组GCS评分:(8±2)分比(6±1)分,(9±4)分比(7±3)分,(11±3)分比(9±2)分,(11±2)分比(9±3)分;CSS评分:(25±4)分比(32±3)分,(25±2)分比(31±5)分,(23±4)分比(29±3)分,(22±3)分比(27±3)分],差异有统计学意义(P〈0.05).结论 在无严重基础疾病的青中年患者,机械胸外按压比徒手胸外按压能更好地改善心脏骤停后综合征.

关 键 词:心肺复苏  心脏骤停后综合征  机械胸外按压

Effect evaluation of mechanical chest compression in patients of post cardiac arrest syndrome
Li Suyan,Zhang Litao,Qi Huijun,Liu Hongying,Si Chongyang.Effect evaluation of mechanical chest compression in patients of post cardiac arrest syndrome[J].China Medicine,2014(3):322-324.
Authors:Li Suyan  Zhang Litao  Qi Huijun  Liu Hongying  Si Chongyang
Institution:Department of Emergency, Hebei General hospital, Shijiazhuang 050051, China.
Abstract:Objective To evaluate the effects of mechanical and manual chest compressions on post cardiac arrest syndrome. Methods Patients with cardiac arrest with restoration of spontaneous circulation in 5-15 minutes were divided into manual cardiopulmonary resuscitation(CPR) group(n=21)and mechanical CPR group (n=23). The data of creatine kinase-MB(CK-MB),cardiac troponin I (cTnI),creatinine(Cr), blood urea nitrogen(BUN) and aspartate transaminase(AST)/alanine aminotransferase(ALT) were recorded after CPR 0, 24,48 h and 72 h. The Glasgow coma scale(GCS) score and european stroke score (CSS) were recorded at CPR 0 h, 24 h,48 h, 7 d and 14 d. Results Compared with manual CPR group,mechanical CPR group yielded lower values of CK-MB,cTnI after CPR 24,48,72 h CK-MB:(80.3±4.5)U/L vs (98.7±8.6)U/L,(40.5±2.8)U/L vs (59.4±3.0)U/L,(30.5±2.9)U/L vs (38.9±3.4)U/L;cTnI:(5.0±0.5)μg/L vs (6.9±0.3)μg/L,(3.8±0.7)μg/L vs (4.9±0.5)μg/L,(1.9±0.5)μg/L vs (2.6±0.4)μg/L] (all P〈0.05).Compared with manual CPR group,mechanical CPR group resulted a higher GCS scoreGCS score:(8±2)scores vs (6±1)scores,(9±4)scores vs (7±3)scores,(11±3)scores vs (9±2)scores,(11±2)scores vs (9±3)scores],a lower CSS score(25±4)scores vs (32±3)scores,(25±2)scores vs (31±5)scores,(23±4)scores vs (29±3)scores,(22±3)scores scores vs (27±3)scores] after CPR 24,48 h and 7 d,14 d (all P〈0.05). Conclusion Mechanical chest compressions alleviates post cardiac arrest syndrome.
Keywords:Cardiopulmonary resuscitation  Post cardiac arrest syndrome  Mechanical chest compressions
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