体重指数对血糖、血脂及血压的影响

目的探讨不同体重指数(BMI)水平对血糖、血脂及血压的影响。方法对1568例年龄≥20岁的健康体检者的资料进行统计学分析,按BMI不同分为四组:G1组(BMI≤18.5 kg/m2)、G2组(18.5 kg/m2BMI≤23.9 kg/m2)、G3组(24 kg/m2≤BMI≤27.9 kg/m2)和G4组(BMI≥28 kg/m2)。结果随BMI逐渐升高,收缩压、舒张压、空腹血糖(FPG)、餐后2 h血糖(PG 2 h)、总胆固醇、甘油三酯(TG)、低密度脂蛋白胆固醇均呈线性上升趋势,而高密度脂蛋白胆固醇呈下降趋势,组间比较差异有统计学意义。在G3组,FPG(6.2 0.4)mmol/L,PG 2 h(8.1 1.3)mmol/L,但血压和TG尚正常,G4组FPG(6.5 0.3)mmol/L,PG 2 h(9.0 1.6)mmol/L,血压均值139.5/88.3 mm Hg(1 mm Hg=0.133 kPa),TG(1.8 1.0)mmol/L。经Logistic逐步回归分析,G3及G4组均与糖尿病、高甘油三酯血症和高血压病呈独立正相关关系。结论 BMI≥24 kg/m2后发生糖尿病、高甘油三酯血症及高血压病的危险性大大增加。

Effect of different BMI level on blood glucose,lipid and blood pressure

Objective To explore the effect of different BMI level on blood glucose,lipid and blood pressure.MethodsClinical data of 1568 subjects aging over 20 years were analyzed.They were divided into 4 groups according to BMI level,which were BMI≤18.5 kg/m^2,18.5-23.9 kg/m^2,24-27.9 kg/m^2 and ≥28 kg/m^2.ResultsWith BMI increasing,the level of fasting plasma glucose（FPG）,2 h-plasma glucose after OGTT（PG 2 h）,blood pressure（BP）,total cholesterol（TC）,triglycerides（TG） and lowdensity lipoprotein-cholesterol（LDL-C） showed a trend of linear increase,but highdensity lipoprotein-cholesterol（HDL-C） showed a trend of linear decrease,and there were significant differences among the groups.The mean FPG and PG 2 h in group with BMI 24-27.9 kg/m^2 reach（6.2±0.4）mmol/L and（8.1±1.3）mmol/L respectively,but BP and TG were still normal range.In group with BMI ≥28 kg/m^2,FPG and PG 2 h were（6.5±0.3）mmol/L and（9.0±1.6）mmol/L respectively,the mean BP was 139.5/88.3 mm Hg（1 mm Hg=0.133 kPa）,the mean fasting TG was（1.82±1.0）mmol/L.Logistic regression analysis showed that BMI in the group of 24-27.9 kg/m^2 and ≥28 kg/m^2 were positively associated with the development of DM,hypertriglyceride and hypertention.ConclusionWhen BMI is over 24 kg/m^2,the risk of development of DM,hypertriglyceride and hypertention should significantly increased.