| 白细胞介素17与妊娠及相关疾病 |
| |
| 引用本文： | 刘凤娟（综述）,董曼岳（审校）. 白细胞介素17与妊娠及相关疾病[J]. 国外医学:妇产科学分册, 2009, 0(2): 140-143 |
| |
| 作者姓名： | 刘凤娟（综述） 董曼岳（审校） |
| |
| 作者单位： | 浙江大学医学院附属妇产科医院; |
| |
| 摘 要： | 白细胞介素17（IL-17）主要由活化的T淋巴细胞产生的促炎性细胞因子发挥免疫调节、促炎症反应、增强滋养细胞浸润性和促进血管新生的作用,在感染性疾病、自身免疫性疾病的免疫病理学中起着重要的作用。人胎盘绒毛滋养细胞、绒毛外滋养细胞和Hofbauer细胞以及鼠蜕膜组织均表达IL-17,而且表达水平呈现动态变化,因此,IL-17可能参与妊娠免疫耐受的调节。对IL-17的研究及其与妊娠和子痫前期的关系作简要综述。
|
| 关 键 词： | 白细胞介素17 细胞因子 妊娠 子痫前期 |
Interleukin-17 in Pregnancy and Gestational Diseases |
| |
| LIU Feng-juan,DONG Min-yue.Women's Hospital,Zhejiang University,School of Medicine,Hangzhou ,China. Interleukin-17 in Pregnancy and Gestational Diseases[J]. Foreign Medical Sciences(Obstet Gynecol Fascicle), 2009, 0(2): 140-143 |
| |
| Authors: | LIU Feng-juan DONG Min-yue.Women's Hospital Zhejiang University School of Medicine Hangzhou China |
| |
| Affiliation: | LIU Feng-juan,DONG Min-yue.Women's Hospital,Zhejiang University,School of Medicine,Hangzhou 31006,China |
| |
| Abstract: | Interleukin-17 （IL-17） is a pro-inflammatory cytokine secreted exclusively by activated T-cells, plays an important role in immunoloregulation, proinflammatory, regulating trophoblast invasion and angiogenesis o IL-17 is also a host mechanism of immunopathology of infectious diseases and auto-immune disease. IL-17 are expressed in placental trophoblast cells, extravillous trophoblast ceils, and placental macrophages （Hofbauer cells）. Moreover, the expression of IL-17 are viable in different phases of pregnancy, IL-17 may involve in immunoregulation in the establishment of pregnancy. In this article, We provide a brief review about interleukin-17 in pregnancy and gestational diseases. |
| |
| Keywords: | Interleukin-17 Cytokine Pregnancy Preeclampsia |
| 本文献已被 CNKI 维普 等数据库收录！ |
|
