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H5N1 highly pathogenic avian influenza virus isolated from conjunctiva of a whooper swan with neurological signs |
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| Authors: | Vuong N. Bui Haruko Ogawa Lai H. Ngo Tugsbaatar Baatartsogt Lary N. B. Abao Shio Tamaki Keisuke Saito Yukiko Watanabe Jonathan Runstadler Kunitoshi Imai |
| Affiliation: | 1. Research Center for Animal Hygiene and Food Safety, Obihiro University of Agriculture and Veterinary Medicine, 2-11 Inada, Obihiro, Hokkaido, 080-8555, Japan 2. Institute for Raptor Biomedicine, Kushiro, Hokkaido, 084-0922, Japan 3. Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA |
| Abstract: | An H5N1 highly pathogenic avian influenza virus was isolated from conjunctiva of a whooper swan with neurological signs, which was captured during the latest H5N1 HPAI outbreak in Japan. The conjunctival swab contained a larger amount of the virus in comparison with the tracheal swab. This is the first report on H5N1 virus isolation from the conjunctiva of a wild bird, and the result may suggest the conjunctival swab to be a critical sample for H5N1 HPAIV detection in waterfowl. Phylogenetic analysis of the HA gene indicated that the virus falls into H5N1 clade 2.3.2.1. |
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