| 木犀草素对大鼠腹腔巨噬细胞释放H_20_2的影响 |
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| 引用本文： | 郑亦文,马东来,陈敏珠. 木犀草素对大鼠腹腔巨噬细胞释放H_20_2的影响[J]. 中国药理学通报, 1990, 0(1) |
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| 作者姓名： | 郑亦文 马东来 陈敏珠 |
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| 作者单位： | 安徽医科大学临床药理研究所，安徽医科大学临床药理研究所，安徽医科大学临床药理研究所 合肥 230032，合肥 230032，合肥 230032 |
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| 摘 要： | 用荧光法研究木犀草素对大鼠腹腔巨噬细胞释放H_2O_2的影响。结果表明,木犀草素在不同浓度(4×10(-7)～10~(-5)mol/L)时,对酵母多糖诱导的大鼠腹腔巨噬细胞H_2O_2释放呈浓度依赖性的抑制,且以木犀草素与巨噬细胞共同培养4h抑制作用最明显。其作用机制有待进一步研究。
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| 关 键 词： | 木犀草素 巨噬细胞 H_2O_2 荧光法 |
EFFECTS OF LUTEOLIN ON H_2O_2 RELEASE OF PERITONEAL MACROPHAGES IN RAT |
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| Zheng Yiwen,Ma Donglai,Chen Minzhu. EFFECTS OF LUTEOLIN ON H_2O_2 RELEASE OF PERITONEAL MACROPHAGES IN RAT[J]. Chinese Pharmacological Bulletin, 1990, 0(1) |
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| Authors: | Zheng Yiwen Ma Donglai Chen Minzhu |
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| Abstract: | Using the fluorescence method, the effect of Luteolin ( Lut) on H2O2 release of peritoneal macrophages(M(?)s) in rat was studied. The results showed that H2O2 release of peritoneal M(?)s stimulated by op-sonized Zymosan was reduced by in vitro treatment of Lut. The inhibitory effect of Lut is in a concentration-dependent manner over the range of 4 × 10-7-10-5mol/L. When M(?)s was cultivated with Lut for 4 h, the inhibitory effect of Lut was the most obvious. |
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| Keywords: | Luteolin Macrophage H_2O_2 Fluorescence |
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