99mTc-MIBI显像对甲状腺结节良恶性的鉴别诊断价值

目的评价99mTc-MIBI(甲氧异腈)显像对鉴别甲状腺结节良恶性的临床价值.方法对122例99mTcO-4显像为结节的患者行99mTc-MIBI动态血流灌注、早期20分钟及延迟2小时静态平面显像.结果99mTc-MIBI动态血流灌注显像诊断甲状腺癌的灵敏度为53.8%(21/39),特异性为75.9%(63/83);早期20分钟静态平面显像诊断甲状腺癌的灵敏度为92.3%(36/39),特异性为60.24%(50/83);延迟2小时静态平面显像诊断甲状腺癌的灵敏度为87.2%(34/39),特异性为85.54%(71/83).5例患者颈部肿大的淋巴结摄取99mTc-MIBI.结论99mTc-MIBI显像对甲状腺结节良恶性的鉴别诊断具有较高的灵敏度和特异性,同时对甲状腺癌转移灶的诊断也有重要价值.

The value of 99mTc-MIBI imaging in differentiation diagnosis of malignant and benign thyroid nodule

Objective To assess the clinical value of 99mTc-MIBI imaging in differentiation diagnosis of malignant and benign thyroid nodule. Methods 122 patients which 99mTcO4 imaging showed nodule were assessed both 99mTc-MIBI thyroid gland dynamic blood stream perfusion imaging and plane static imaging after 20 minutes and 2 hours. Results The sensitivity of 99mTc-MIBI dynamic imaging in diagnosis of thryoid cancer was 53.8% , and the specificity was 75.6% . The sensitivity of 99mTc-MIBI imaging after 20 minutes in diagnosis of thyroid cancer was 92.3%, and the specificity was 60.24%. The sensitivity of 99mTc-MIBI imaging after 2 hours in diagnosis of thyroid cancer was 87.2%, and the specificity was 85.54% . Conclusion 99mTc-MIBI imaging gave a good sensitivity and speificity in differentiation diagnosis of thyroid nodule.