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| 高渗碳酸氢钠静脉注射对出血性休克狗血流动力学的影响 | |
| 引用本文： | 肖家彬,王焱林,万德宁,李翠荣,唐宏刚. 高渗碳酸氢钠静脉注射对出血性休克狗血流动力学的影响[J]. 武汉大学学报(医学版), 1992, 0(2) |
| 作者姓名： | 肖家彬 王焱林 万德宁 李翠荣 唐宏刚 |
| 作者单位： | 湖北医学院附二医院麻醉科，湖北医学院附二医院麻醉科，湖北医学院附二医院麻醉科，湖北医学院附二医院麻醉科，湖北医学院附二医院麻醉科 |
| 摘 要： | 本实验对6只出血性休克复苏后狗快速静注高渗碳酸氢钠后血流动力学反应进行了研究。5%NaHCO_3(1mmol/kg)静注后立即出现平均主动脉压下降,心率增快,注射后50s MAP、HR 恢复到注射前水平,然后血压逐渐升高,心输出量、平均肺动脉压和肺小动脉楔压,不同程度增高,外周血管阻力则比注射前降低,而且休克后仍存在的代谢性酸中毒得到显著改善。作者建议高渗碳酸氢钠静注速度宜慢,以防一过性低血压的发生。 |
| 关 键 词： | 碳酸氢盐类/生理学 血流动力学 |
Hemodynamic Effects of Rapid Intravenous Injection of Hypertonic Sodium Bicarbonate |
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| Xiao jiabin Wang Yanlin Wan Dening. Hemodynamic Effects of Rapid Intravenous Injection of Hypertonic Sodium Bicarbonate[J]. Medical Journal of Wuhan University, 1992, 0(2) | |
| Authors: | Xiao jiabin Wang Yanlin Wan Dening |
| Affiliation: | Xiao jiabin Wang Yanlin Wan Dening Department of Anesthesiology,Second Affiliated Hospital,Hubei Medical College,Wuhan 430071,China |
| Abstract: | The hemodynamic effects of rapid intravenocs injection of hypertonic sodium bicarbonate(5% NaHCO_3)following resuscitation of hemorrhagic shock were studied in 6 dogs.It was demonstrated that 5% NaHCO_3 injection(1 mmol/Kg)resulted in transcient MAP decrease and HR increase for 50 seconds immediately after injection,followde by MAP,CO,MPAP and PCWP increases and SVR de- crease in variable degree.Metabolic acidosis still existed after shock resuscitation was significantly im- proved,It is suggested that 5% NaHCO_3 be slowly given to prevent transcient hypotension from occur- ing. |
| Keywords: | MeSH bicarbonates/PH hemodynamics |
| 本文献已被 CNKI 等数据库收录！ | |