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| 酒石酸二氢可待因控释片对晚期癌痛病人镇痛效果临床评价 | |
| 引用本文： | 徐国柱,段砺瑕,刘亚利,刘淑俊,许立功,侯浚,邓艳萍,蔡志基. 酒石酸二氢可待因控释片对晚期癌痛病人镇痛效果临床评价[J]. 中国药物依赖性杂志, 1999, 8(1): 52-57 |
| 作者姓名： | 徐国柱 段砺瑕 刘亚利 刘淑俊 许立功 侯浚 邓艳萍 蔡志基 |
| 作者单位： | 1. 北京医科大学中国药物依赖性研究所,北京,100083 2. 湖南省肿瘤医院,长沙,410006 3. 北京医科大学肿瘤医院,北京,100036 4. 上海医科大学肿瘤医院,上海,200032 5. 河北省肿瘤研究所,石家庄,050011 |
| 摘 要： | 应用酒石酸二氢可待因控释片（简称控释片）与酒石酸二氢可待因普通片（简称普通片）随机双盲对照试验，对晚期癌症伴有中、重度疼痛的患者进行镇痛效果及不良反应观察。结果表明：控释片每１２ｈ口服一次可以有效控制晚期癌症慢性中度以上疼痛。与普通片相比较，镇痛效果在日剂量相同的情况下，组间差异无显著性。控释片的不良反应主要有头晕、恶心、呕吐等，与普通片相比，组间差异无显著性 |
| 关 键 词： | 酒石酸二氢可待因控释片；酒石酸二氢可待因普通片；镇痛药物评价 |
CLINICAL EVALUATION OF ANALGESIC EFFECT OF DIHYDROCODEINE TARTRATE CONTROLLED RELEASE TABLETS IN CANCER PAIN |
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| Xu Guozhu,Duan Lixia,Liu Yali,Liu Shujun,Xu Ligong,Hou Jun,Deng Yanping,Cai Zhiji. CLINICAL EVALUATION OF ANALGESIC EFFECT OF DIHYDROCODEINE TARTRATE CONTROLLED RELEASE TABLETS IN CANCER PAIN[J]. Chinese Journal of Drug Dependence, 1999, 8(1): 52-57 | |
| Authors: | Xu Guozhu Duan Lixia Liu Yali Liu Shujun Xu Ligong Hou Jun Deng Yanping Cai Zhiji |
| Abstract: | A randomized and double-blind clinical trial of the analgesic effect of dihydrocodeine tartrate controlled release tablets (CDHC) was carried out on cancer patients in terminal state with moderate and severe pain. Dihydrocodeine tartrate immediate-release tablets (IDHC) was used as positive control. Results indicated that CDHC was effective in the control of moderate to severe cancer-related pain while administered every 12 hours, there was no significant difference between CDHC and IDHC. The adverse drug reactions of CDHC and IDHC showed the same profile, they were dizziness, nausea and vomiting . |
| Keywords: | dihydrocodeine tartrate controlled release tablets dihydrocodeine tartrate immediate-release tablets clinical evaluation of analgesic effect |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |