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经皮椎体成形术治疗疼痛性骨质疏松性胸腰椎压缩骨折
引用本文:刘宏建,杜靖远,韩松辉,梁惠民,刘昌盛.经皮椎体成形术治疗疼痛性骨质疏松性胸腰椎压缩骨折[J].华中科技大学学报(医学版),2004,33(4):481-484.
作者姓名:刘宏建  杜靖远  韩松辉  梁惠民  刘昌盛
作者单位:1. 华中科技大学同济医学院附属协和医院骨科,武汉,430022
2. 河南省洛阳正骨医院正骨研究所影像中心,洛阳,471002
3. 华中科技大学同济医学院附属协和医院介入放射科,武汉,430022
4. 上海瑞邦生物材料有限公司,上海,200237
摘    要:目的 观察经皮椎体成形术 (PVP)治疗疼痛性骨质疏松性胸腰椎压缩骨折的初步临床疗效并分析其止痛机制。方法 自 2 0 0 3年 1月~ 2 0 0 3年 11月 ,使用自固化磷酸钙人工骨 (CPC)为充填材料 ,在透视监视下 ,经单侧或双侧椎弓根穿刺行椎体成形术治疗 2 3例 31个骨质疏松性胸腰椎压缩骨折的椎体。结果 CPC平均充填量胸椎 3 1ml,腰椎 4 0ml;术中CPC渗漏者 4例 4个椎体 ,但无 1例出现严重并发症。术后根据Huskisson目测疼痛评分法(VAS)评定 ,并经 3~ 10个月 (平均 6 6个月 )的随访 ,术后所有患者疼痛明显减轻或消失 (P <0 0 1)。结论 PVP可安全有效地缓解骨质疏松性胸腰椎压缩骨折引起的疼痛。

关 键 词:经皮椎体成形术  自固化磷酸钙人工骨  骨质疏松症  脊柱骨折
修稿时间:2004年1月21日

Percutaneous Vertebroplasty for Treatment of Painful Osteoporotic Thoracolumbar Vertebral Compression Fracture
Liu Hongjian,Du Jingyuan,Han Songhui et al.Percutaneous Vertebroplasty for Treatment of Painful Osteoporotic Thoracolumbar Vertebral Compression Fracture[J].Journal of Huazhong University of Science and Technology(Health Sciences),2004,33(4):481-484.
Authors:Liu Hongjian  Du Jingyuan  Han Songhui
Institution:Liu Hongjian1,Du Jingyuan1,Han Songhui2 et al 1 Department of Orthopaedics,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430022 2 The Imaging Center of Luoyang Orthopaedic Hospital,Luoyang Institute of Traditional Chinese Orthopedics and Traumatology of Henan Province,Luoyang 471002
Abstract:Objective To investigate the clinical effectiveness of percutaneous vertebroplasty (PVP) in the treatment of painful osteoporotic thoracolumbar vertebral compression fracture. Methods From Jan. 2003 to Nov. 2003, under C-arm fluoroscopy monitoring, 31 consecutive PVP procedures through unilateral or bilateral verterbral pedicles with autosolidification calcium phosphate cement (CPC) were performed on 23 patients with painful osteoporotic thoracolumbar vertebral compression fracture. Results The average injection dose of CPC was 3.1 ml for thoracic and 4.1 ml for lumbar vertebrae. Cement leakage occurred during the procedure at 4 levels. All patients had successful intervention and marked or complete pain relief assessed by the visual analogue scale (VAS) (P<0.01), and were followed up with the range 3-10 months. There was no severe complication related to this treatment.Conclusion PVP is safe and effective, and has a useful role in the treatment of painful osteoporotic vertebral compression fractures.
Keywords:percutaneous vertebroplasty  calcium phosphate cement  osteoporosis  spine fracture
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