针刺干预大鼠实验性脑梗塞的形态学研究——Ⅰ软脑模动脉网的代偿及动态定量观察 |
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引用本文: | 翟娜,杜元灏,石学敏,许屏. 针刺干预大鼠实验性脑梗塞的形态学研究——Ⅰ软脑模动脉网的代偿及动态定量观察[J]. 针刺研究, 1993, 0(1) |
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作者姓名: | 翟娜 杜元灏 石学敏 许屏 |
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作者单位: | 天津中医学院第一附属医院,天津中医学院第一附属医院,天津中医学院第一附属医院,天津第二医学院组胚 300193,300193,300193 |
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摘 要: | 以脑灌注方法动态观察了阻断大鼠一侧大脑中动脉(MCA_0)所致大脑表面缺血区内软脑膜动脉网的代偿及针刺效应。MCA_0阻断后立即灌注,整个阻断侧大脑半球为空白的缺血区;阻断 MCA_03小时后,针刺组缺血区边缘末梢吻合网的血流已部分涌入缺血区,并随时间延长,缺血区内充盈血管逐渐增多,而非针刺组仅可见到缺血区内有个别的代偿血管。实验提示:阻断 MCA_0初期,MCA 血管系统存在较严重的血管痉挛,故旁侧动脉的代偿基本不能实现,针刺则在缺血早期快速缓解了血管痉挛,使之接受代偿血流。
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关 键 词: | 脑灌注 大脑中动脉 脑梗塞 软脑膜动脉网 针刺 |
MORPHOLOGICAL STUDY ON ACUPUNCTURE IN INTERFERING EXPERIMENTAL CEREBRAL INFARCTION IN RAT——Ⅰ.Compensation of Cerebal PIA Mater Artery in Cerebral Surface |
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Abstract: | Occluding unilateral middle cerebrarl artery (MCAo) of rat,the compensatoryblood vessels (CBV) within ischemic area in cerebral surface shown by cerebralperfusion and effect of acupuncture were observed dynamically.Perfusing im-mediately after MCAo,there was no any blood vessel in the ischemic area.Inacupuncture group,the CBV had extended a lot from anastomotic network ofcerebral pin mater (ACA-MCA,PCA-MCA) located in marginal zone of ischemicarea 3 hs after MCAo.6,24 and 48 hs after MCAo,the CBV increased muchmore than control group (non-acupuncture) P<0.01.The experiment pointed outthat there existed a serious vasospasm in the MCA system in initial stage ofMCAo,which led up to decompensation in the ischemic area.The acupuncturecan remit the vasospasm,and reverse the deteriorated process in early. |
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