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| mTOR信号通路与胃癌复发转移关系的研究进展 | |
| 引用本文： | 朱优龙 综述姜波健,俞继卫审校. mTOR信号通路与胃癌复发转移关系的研究进展[J]. 中国普通外科杂志, 2013, 22(4): 489-493 |
| 作者姓名： | 朱优龙 综述姜波健 俞继卫审校 |
| 作者单位： | 朱优龙 (上海交通大学医学院附属第三人民医院普外一科,上海,201999); |
| 基金项目： | 国家自然科学基金资助项目(项目编号：81101850),上海市教委基金资助项目(项目编号：12YZ047) |
| 摘 要： | mTOR及其信号通路在胃癌的复发和转移过程中起重要作用,以mTOR为靶点的靶向药物联合化疗药物对于克服胃癌复发及转移治疗胃癌具有广阔的临床应用前景。笔者就国内、外近年来有关mTOR信号通路在胃癌复发转移中作用机制的研究进展作一综述。 |
| 关 键 词： | 胃肿瘤 mTOR 肿瘤复发 肿瘤转移 综述文献 |
| 收稿时间： | 2012-08-18 |
| 修稿时间： | 2013-03-03 |
Relations of mTOR signal pathway with recurrence and metastasis of gastric cancer: recent progress |
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| ZHU Youlong,JIANG Bojian,YU Jiwei. Relations of mTOR signal pathway with recurrence and metastasis of gastric cancer: recent progress[J]. Chinese Journal of General Surgery, 2013, 22(4): 489-493 | |
| Authors: | ZHU Youlong JIANG Bojian YU Jiwei |
| Affiliation: | (The First Department of General Surgery, No.3 People’s Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 201999, China) |
| Abstract: | mTOR and its signal pathway components are closely related to recurrence and metastasis of gastric cancer, so the targeted drugs against mTOR combined with chemotherapy agents show great application potentials for avoiding the recurrence and metastasis of gastric cancer. In this paper, the authors present the recent progress in the mechanisms underlying mTOR signaling pathway-mediated recurrence and metastasis of gastric cancer. |
| Keywords: | Stomach Neoplasms mTOR Neoplasm Recurrence Neoplasm Metastasis Review |
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