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卒中后轻度认知功能障碍与脑白质病变的研究
引用本文:李广生,杨淞然,潘小平. 卒中后轻度认知功能障碍与脑白质病变的研究[J]. 中国卒中杂志, 2012, 7(9): 747-752
作者姓名:李广生  杨淞然  潘小平
作者单位:广州医学院附属广州市第一人民医院神经科
基金项目:国家自然科学基金(青年基金):额叶纹状体环路损伤与卒中后抑郁伴执行功能障碍的关系(81000508)广州市-伯明翰大学脑与认知中心
摘    要:
脑白质病变,在影像学中又称为脑白质疏松症,是脑微血管病变的一种重要类型。有大量研究表明,卒中后轻度认知功能障碍与脑白质病变存在明显的相关性。弥散张量成像对白质纤维的显示具有一定的优势,成为卒中后认知功能障碍研究的重要工具。本文对近年来卒中后认知功能障碍与脑白质病变的相关研究予以综述。

关 键 词:卒中  轻度认知功能障碍  脑白质病变  弥散张量成像  
收稿时间:2012-04-23

Study on Mild Cognitive Impairment after Stroke and White Matter Lesions
LI Guang-Sheng,YANG Song-Ran,PAN Xiao-Ping. Study on Mild Cognitive Impairment after Stroke and White Matter Lesions[J]. Chinese Journal of Stroke, 2012, 7(9): 747-752
Authors:LI Guang-Sheng  YANG Song-Ran  PAN Xiao-Ping
Affiliation:. (Department of Neurology, Guangzhou First Municipal People's Hospital Affiliated to Guangzhou Medical University, Guangzhou 510180, China)
Abstract:
White matter lesions, leukoaraiosis on structural magnetic resonance imaging, is an important type of cerebral small-vessel disease. Plenty of studies have shown that cognitive impairment is closely associated with white matter lesions. Diffusion tensor imaging, which can detect microstructural changes in pathological processes, has become an important tool in the assessment of cognitive impairment after stroke. In this paper the association between mild cognitive impairment after stroke and white matter lesions in recent years was reviewed.
Keywords:Stroke  Mild cognitive impairment  White matter lesions  Diffusion tensor imaging
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