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中药抗肺癌转移机制的实验研究进展
引用本文:吴建春,李雁. 中药抗肺癌转移机制的实验研究进展[J]. 辽宁中医药大学学报, 2009, 0(4)
作者姓名:吴建春  李雁
作者单位:上海中医药大学附属上海市中医医院肿瘤科;
基金项目:上海市教委自然科学基金资助项目(05CZ33);;上海市申康医院发展中心中医肿瘤特色专科基金资助项目(SHDC12007303)
摘    要:肺癌是最常见的恶性肿瘤之一,肺癌转移是导致治疗失败甚至死亡的主要原因。本文概述了近年来中医药抗肺癌转移机制的实验进展情况,表明中医药可以从肺癌转移的多个环节如抑制原发瘤的生长,改变细胞的黏附性,抑制基底膜的降解,抑制肿瘤血管的形成,调节转移相关基因的表达等方面进行调控。并对当前存在的问题做了扼要分析。提示中药抗肺癌转移具有广阔的前景,值得更深入规范的研究。

关 键 词:中医药  肺癌  转移机制  实验研究  综述  

Experimental Study Progress on the Mechanism of TCM Anti-lung Cancer Metastasis
WU Jian-chun,LI Yan. Experimental Study Progress on the Mechanism of TCM Anti-lung Cancer Metastasis[J]. Journal of Liaoning University of Traditional Chinese Medicine, 2009, 0(4)
Authors:WU Jian-chun  LI Yan
Affiliation:Oncology Department of Shanghai City's Hospital of TCM attached to Shanghai University of TCM;Shanghai 200071;China
Abstract:The lung cancer is one of most common malignant tumors;the lung cancer metastasis is the primary reason which causes the treatment defeat even dies.This article outlined the experimental progress on the traditional Chinese medicine inhibiting lung cancer metastasis in recent years,indicating that it can work from many aspects of the lung cancer metastasis,such as inhibiting the primary tumor growth,changing the cell's adhesion,suppressing the degeneration of the basement membrane,suppressing the formation o...
Keywords:TCM  lung cancer  metastasis  experimental study  review  
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