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| 心脏螺旋波演化与驱动的计算机实验 | |
| 引用本文： | 刘丽,李莉,张广才,王光瑞,曲直. 心脏螺旋波演化与驱动的计算机实验[J]. 生物医学工程学杂志, 2007, 24(3): 485-487 |
| 作者姓名： | 刘丽 李莉 张广才 王光瑞 曲直 |
| 作者单位： | 1. 中国医科大学,生物物理教研室,沈阳,110001;辽宁大学,物理系,实验物理教研室,沈阳,110022 2. 中国医科大学,生物物理教研室,沈阳,110001 3. 北京应用物理与计算数学研究所,北京,100088 |
| 基金项目： | 国家自然科学基金;辽宁省沈阳市科技计划 |
| 摘 要： | 我们利用FitzHugh-Nagumo(FHN)类型方程,对二维心肌可激媒质系统螺旋波(Spiral wave,SW)的形成、演化和控制进行了数值模拟,主要有以下研究结果:(1)改变系统的可激性,不会影响SW的激发区宽度,却改变SW的自转周期和旋波核的大小;当可激性达到某一极限值时,SW的自转周期与旋波核的半径趋于无穷大,系统不再出现SW。(2)对SW的均匀近共振小电流驱动,可以引导旋波头(Spiral wave tip,SWT)的漂移运动;当驱动频率接近SW的自转频率时,SWT会沿着圆周漂移,当驱动频率达到共振频率时,SWT会沿着直线漂移。 |
| 关 键 词： | 螺旋波 旋波头 旋波核 近共振驱动 |
| 修稿时间： | 2004-05-252006-11-16 |
Numerical Simulation on Evolution and Control of Spiral Wave in Heart |
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| Liu Li,Li Li,Zhang Guangcai,Wang Guangrui,Qu Zhi. Numerical Simulation on Evolution and Control of Spiral Wave in Heart[J]. Journal of biomedical engineering, 2007, 24(3): 485-487 | |
| Authors: | Liu Li Li Li Zhang Guangcai Wang Guangrui Qu Zhi |
| Affiliation: | 1.Department of Biophysics, China Medical University, Shenyang 110001,China; 2.Department of Physics, Liaoning University, Shenyang 110022,China; 3.Institute of Applied Physics and Computational Mathematics, Beijing 100088,China |
| Abstract: | In this paper,the numerical simulation for evolution and control of spiral waves in 2D cardiac excitable media is performed;it can be represented as modified FitzHugh-Nagumo(FHN)model by selecting suitable parameter values.When the plane wave being cut,the system can evolve into a spiral wave.The excitability of media can produce effect on the stability of spiral wave.When the excitability is greater than the critical value,the spiral wave core and period tend towards infinity and disappear.The drifting ways of spiral wave tip are different(meandering)in various driving frequencies when one spiral wave is driven by uniform periodic small current.When period T is below or above the resonance period of spiral wave,the spiral wave is in its pedaflower or pediflower orbit,and if the driving period precisely equals the resonance period,the spiral wave tip drifts along a straight line. |
| Keywords: | Spiral wave Spiral wave tip Spiral wave core Near resonance drive |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |