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雷尼替丁对支气管哮喘患者气道反应性的影响
引用本文:江山平,刘启良,梁永康.雷尼替丁对支气管哮喘患者气道反应性的影响[J].中山大学学报(医学科学版),1996(3).
作者姓名:江山平  刘启良  梁永康
作者单位:中山医科大学孙逸仙纪念医院呼吸内科
基金项目:孙逸仙纪念医院科研基金
摘    要:通过食管吞钡X线及食管内窥镜检查选择支气管哮喘(简称哮喘)伴胃食管反流疾病(GERD)者13例(GERD阴性组),哮喘不伴GERD者14例(GERD阴性组),均给予口服雷尼替丁,每次150mg,每日2次,疗程8周。结果显示:雷尼替丁治疗后,GERD阴性组哮喘临床积分显著增高。FVC%Pred、FEV1、FEV1/FVC、V50、V25、组胺PC20-FEV1,均显著降低;GERD阳性哮喘临床积分显著降低,VC、VC%Pred、FVC、FVC%Pred、FEV1、FEV1/FVC、V50、V25、组胺PC20-FEV1、均显著增高。表明雷尼替丁对哮喘患者气道反应性的影响与患者是否合并GERD有关。

关 键 词:哮喘/药物疗法,胃食管反流/药物疗法,雷尼替丁/药理学

THE DIAGNOSTIC VALUE OF PROLONGATION OF Q Tc INTERVAL IN IDENTIFYING MYOCARDIAL ISCHEMIA BY AMBULATORY ELECTROCARDIOGRAM
Gao Xiuren,Zheng Zhensheng,Ma Hong,Wang Yesong,Liu Jun.THE DIAGNOSTIC VALUE OF PROLONGATION OF Q Tc INTERVAL IN IDENTIFYING MYOCARDIAL ISCHEMIA BY AMBULATORY ELECTROCARDIOGRAM[J].Journal of Sun Yatsen University(Medical Sciences),1996(3).
Authors:Gao Xiuren  Zheng Zhensheng  Ma Hong  Wang Yesong  Liu Jun
Abstract:The Changs of ST Segment and Q Tc interval in 186 consecutive patients with documented myocardial infarction and 50 normal subjects were studied during ambulatory electrocardiogram monitoring.For indentifying myocardial ischemia,the sensitivity and specificity of Q Tc interval positive were 92.5% and 96.0% respectively.While the sensitivity and specificity of ST segment changes were 69.4% and 100.0% respectively.The sensitivity had significantly difference in two groups by statistics( P <0.01),and there were no any difference in two groups in the specificity by statistics( P >0.05).The results indicate that the Q Tc interval can be used as one of the indices of myocardial ischemia.
Keywords:lectrocardiography  ambulatory  myocardial infarction/diagnosis  myocardial ischemia/diagnosis  
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