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| 单克隆抗体MG9用于肺癌的免疫组化研究 | |
| 引用本文： | 戴文森 陈菊荣. 单克隆抗体MG9用于肺癌的免疫组化研究[J]. 肿瘤, 1993, 13(3): 128-129,145 |
| 作者姓名： | 戴文森 陈菊荣 |
| 作者单位： | 徐州市第四人民医院病理科(戴文森，陈菊荣，宋永谦)，徐州市第四人民医院病理科(党宏) |
| 基金项目： | 徐州市青年医学科研资助课题 |
| 摘 要： | 用鼠抗人胃癌单克隆抗体MG_9对147例不同组织学类型的肺癌进行了免疫组织化学研究,探讨MG_9相关抗原在肺癌组织中的表达及其临床意义。结果表明,肺癌MG_9相关抗原表达总阳性率为51.7％(76/147);不同组织学类型肺癌间阳性率差异显著,其中腺癌阳性率92.1％(47/51),显著高于鳞癌的30.2％(13/43)和小细胞癌的30.2％(16/53),P<0.001。这提示:单抗MG_9对肺腺癌有较高特异性,可作为肺腺癌的一种新的标志物。 |
| 关 键 词： | 免疫组织化学 肺肿瘤 单克隆抗体 |
Immunohistochemical Study of Monoclonal Antibody MG9 in Human Lung Cancer |
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| Dai Wensen,et al.. Immunohistochemical Study of Monoclonal Antibody MG9 in Human Lung Cancer[J]. Tumor, 1993, 13(3): 128-129,145 | |
| Authors: | Dai Wensen et al. |
| Affiliation: | Dai Wensen,et al. Dept. of Pathology,4th People's Hospital of XuZhou,XuZhou |
| Abstract: | The lung cancer(147 cases) were studies using monoclonal antibody MG9 agai-nst gastric carcinoma by Avidin-Biotin peroxidase complex (ABC) method. The resu-Its showed that the total positive rates were 51.7%(76/147). The expression of MG9 related antigen in lung adenocarcinoma were 92.1% (47/51), and 30.2% (13/43) insquamous cell carcinoma and 30.2%(61/53) in small cell cancer. These data suggestthat monoconlal antibody MC9 could be a new tumor marker for adenocarcinomaof the lung. |
| Keywords: | Lung cancer Monoclonal Antibody MG9 Immunohistochemistry |
| 本文献已被 CNKI 维普 等数据库收录！ | |