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| 原发性肝癌患者血清丙型肝炎病毒抗体测定及其临床意义 | |
| 引用本文： | 陈士葆 沈健伟. 原发性肝癌患者血清丙型肝炎病毒抗体测定及其临床意义[J]. 肿瘤, 1993, 13(4): 171-173 |
| 作者姓名： | 陈士葆 沈健伟 |
| 作者单位： | 第二军医大学附属长征医院消化内科，第二军医大学附属长征医院消化内科 教授、主任医师、消化内科主任 |
| 摘 要： | 作者应用抗丙型肝炎病毒(HCV)酶联免疫分析(EIA)试剂盒,对50例原发性肝细胞癌(HCC)患者作了抗HCV检测;同时以40例健康成年献血员作为对照组。血清抗HCV罹患率在对照组为5％(2/40),而在HCC组为10％(5/50)。两组之间无明显差异(P>0.05),但HCC组5例抗HCV阳性者均伴有HBV感染。因此建议今后在对健康献血员作肝功能及HBV系列测定的同时,应作抗HCV测定;对抗HCV阳性者,应进一步作HCV的PCR检测,并应极治疗。 |
| 关 键 词： | 原发性肝细胞癌 抗HCV 酶联免疫分析 |
The Prevalence of Hepatitis C Virus Antibody in Patients with Hepatocellular Carcinoma |
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| Chen Shi-boa et al,Chang-Zheng Hospital,Shanghai. The Prevalence of Hepatitis C Virus Antibody in Patients with Hepatocellular Carcinoma[J]. Tumor, 1993, 13(4): 171-173 | |
| Authors: | Chen Shi-boa et al Chang-Zheng Hospital Shanghai |
| Abstract: | The prevalence of antibody to hepatitis C virus (HCV) was measured in 50 pa-tients wth hepatocellular carcinoma (HCC) using a commercially available enzymeimmunoassay, and 40 samples from blood donors used as control. The overall prevalence of antibody to HCV was 5.0%(2 cases) among 40 unselected blood donors andin 10.0%(5/50) of patients with HCC. The positive cases of anti-HCV occurred onlyin HBV iufected HCC patients. No correlation was found between the prevalence ofanti-HCV in HCC and blood donor (P>0.05). The true prevalence of anti-HCV inpatients with chronic liver disease and HCC may have to be revised when more speci-fic assays become available. HCV should be examined among blood donors just thesame as the HBV series, and anti-HCV positive patients must be treated actively. |
| Keywords: | Primary hepatocellular carcinoma Anti-HCV Enzyme immunoassay |
| 本文献已被 CNKI 维普 等数据库收录！ | |