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HPLC法测定甲硝唑片的含量
引用本文:赵凤菊. HPLC法测定甲硝唑片的含量[J]. 中国中医药杂志, 2008, 6(12): 4-6
作者姓名:赵凤菊
作者单位:云南省大理州食品药品检验所,671000
摘    要:
目的:本文建立测定甲硝唑片的高效液相色谱法。方法:采用XDB柱,流动相为:甲醇-水(20:80)的反高效液相色谱系统。结果:甲硝唑在33.28—332.8ug范围内呈良好的线性关系,相关系数为0.9999,平均回收率为99.8%。结论:本方法简便,准确,重复性好,可用于甲硝唑片含量测定。

关 键 词:甲硝唑片  反高效液相色谱法  甲硝唑

Determination of Metronidazole in Metronidazole Tablets by HPLC
Zhao Fengju. Determination of Metronidazole in Metronidazole Tablets by HPLC[J]. , 2008, 6(12): 4-6
Authors:Zhao Fengju
Affiliation:Zhao Fengju (Dali Prefecture Institute for Drug Control, Yunnan Province, 671000 )
Abstract:
Objective: RP-HPLC method was established for the determination of Metronidazole in Metronidazole Tablets. METHODS: XDB column was used with methanol and water (20:80) as mobile phase . RESSULTS:There was a good linear relationship ( r=0. 9999)when Metronidazole was between33.2ug to332.8ug. The average recovery was99.8%. The method was simple and convenient, accurate and feasible. CONCLUSION:It could be used in thedetermination of Paracetamol in Fen An Jia Min Granules .
Keywords:Granules  RP-HPLC  Metronidazole
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