Autoradiographic localization of [3H]buspirone binding sites in rat brain |
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Authors: | P Kaulen G Brüning U Schneider H G Baumgarten |
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Affiliation: | Department of Anatomy, Free University of Berlin, Königin-Luise-Strasse 15, D-1000 Berlin 33 F.R.G. |
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Abstract: | In the C-neurons of rabbit nodose ganglion there is a persistent slow outward current at Vm levels positive to -80 mV. This current was detectable in Na+-free Ringer and disappeared in Ca2+-free medium. Therefore it may be the Ca2+-activated K+ current. This K+ current shows a unique time and voltage dependency, suggesting that it may have a regulatory role on the excitability of C-neurons. Two other types of current also observed in C-neurons were IQ- and IA-like currents. In A-neurons, however, a Ca2+-activated K+ current was not observed at all. |
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Keywords: | anxiolytic drugs rat brain autoradiography dopamine receptors serotonin receptors |
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