|
|||||
|
|
| 烟酸分子印迹聚合物的制备 | |
| 引用本文： | 蒲家志,汤又文,胡小刚,黄招发,颜景辉. 烟酸分子印迹聚合物的制备[J]. 华西药学杂志, 2004, 19(2): 84-87 |
| 作者姓名： | 蒲家志 汤又文 胡小刚 黄招发 颜景辉 |
| 作者单位： | 华南师范大学化学系,广东广州,510631;遵义医学院基础化学教研室,贵州遵义,563003;华南师范大学化学系,广东广州,510631 |
| 基金项目： | 贵州省科学基金资助课题,黔基台计号:(2003)3009号。 |
| 摘 要： | 目的以烟酸(Nicotinic acid)为模板分子，合成烟酸分子印迹聚合物(MIP)。方法分别研究不同的聚合方法、溶剂对合成烟酸MIP的影响，并通过Scatchard方程分析烟酸MIP的结合特性。结果采用4-乙烯基吡啶和极性较小的氯仿溶剂，合成的模板分子聚合物具有较高的选择性。结论烟酸MIP可用于临床上烟酸的富集和检测。 |
| 关 键 词： | 烟酸 4-乙烯基吡啶 分子印迹聚合物 富集 检测 |
| 文章编号： | 1006-0103(2004)02-0084-04 |
| 修稿时间： | 2003-09-01 |
Synthesis of molecular imprinting polymer for Nicotinic acid |
|
| PU Jia - zhi,TANG You - wen,HU Xiao - gang,HUANG Zhao - fa,YAN Jing - hui. Synthesis of molecular imprinting polymer for Nicotinic acid[J]. West China Journal of Pharmaceutical Sciences, 2004, 19(2): 84-87 | |
| Authors: | PU Jia - zhi TANG You - wen HU Xiao - gang HUANG Zhao - fa YAN Jing - hui |
| Abstract: | OBJECTIVE To synthsize a molecular imprinting polymer with Nicotinic acid as template.METHODS Different polymerization methods and different solvents were investigated to synthsize the imprinted polymer and the binding characteristics of the template polymer were evaluated by Scatchard analysis. RESULTS The polymer taking 4 - vinylpyndine as functional monomer and chloroform as solvent obtained higher selectivity for Nicotinic acid. CONCLUSION Molecularly imprinted polymer will exhibit practical utility for enrichment and determination of trace Nicotinic acid. |
| Keywords: | Nicotinic acid 4- Vinylpvridine Molecular imprinting polymer Enrichment Determination |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |