| Institution: | 1. Division of Pulmonary, Allergy and Sleep Medicine, Mayo Clinic, Jacksonville, FL;2. Department of Critical Care Medicine, Mayo Clinic, Jacksonville, FL;3. Department of Cardiovascular Medicine, Mayo Clinic, Jacksonville, FL;4. Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN;5. Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN;6. Division of Pulmonary Medicine, Mayo Clinic, Scottsdale, AZ;7. Department of Critical Care Medicine, Mayo Clinic, Scottsdale, AZ;1. Resident in Internal Medicine, Mayo Clinic School of Graduate Medical Education, Jacksonville, FL;2. Advisor to residents and Consultant in Gastroenterology and Hepatology, Mayo Clinic, Jacksonville, FL;1. John Ochsner Heart and Vascular Institute, Ochsner Clinic Foundation, New Orleans, LA;2. Department of Medicine, Ochsner Clinic Foundation, New Orleans, LA;3. University of Queensland School of Medicine, Brisbane, Australia;4. Department of Medicine, University of Central Florida School of Medicine, Orlando, FL;1. Department of Cardiology, Mount Sinai Morningside Hospital, Mount Sinai Heart, Icahn School of Medicine at Mount Sinai, New York, NY;2. Department of Cardiovascular Diseases, John Ochsner Heart and Vascular Institute, Ochsner Clinical School-the UQ School of Medicine, New Orleans, LA;3. Department of Imaging and Department of Medicine, Burns and Allen Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA;1. Division of Gastroenterology and Hepatology, Department of Medicine, Northwestern University Feinberg School of Medicine, 676 North St Clair Street, Suite 1400, Chicago, IL 60611, USA;2. Division of Epidemiology, Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA |
| Abstract: | Pulmonary hypertension is a complex condition but a relatively common manifestation of severe cardiopulmonary disease. By contrast, pulmonary arterial hypertension is uncommon and is more prevalent in young women. To better categorize patients and to guide clinical decision-making, 5 diagnostic groups and associated subgroups characterize the spectrum of disease. A multidisciplinary approach to evaluation and treatment is recommended by published guidelines and often entails referral to a designated pulmonary hypertension center. Several key publications during the last couple of years merit review. The PubMed database was searched for English-language studies and guidelines relating to pulmonary hypertension. The following terms were searched, alone and in combination: pulmonary hypertension, pulmonary arterial hypertension, portopulmonary hypertension, and chronic thromboembolic pulmonary hypertension. The focus was on those publications with new information on evaluation and management of pulmonary hypertension between January 1, 2019, and January 31, 2021. Of the subgroups, 2 were of particular interest for this review: portopulmonary hypertension and chronic thromboembolic pulmonary hypertension. Last, available data on the impact of the coronavirus disease 2019 pandemic and newer treatment agents in early trials were selectively reviewed. The review is therefore intended to serve as a practical, focused review of important topics germane to those clinicians caring for patients with pulmonary hypertension. |
