Clinical course of COVID-19 patients treated with ECMO: A multicenter study in Daegu,South Korea |
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| Affiliation: | 1. Department of Thoracic and Cardiovascular Surgery, Keimyung University Dongsan Hospital, Keimyung University College of Medicine, Daegu, Republic of Korea;2. Department of Thoracic and Cardiovascular Surgery, Keimyung University Daegu Dongsan Hospital, Keimyung University College of Medicine, Daegu, Republic of Korea;3. Department of Thoracic and Cardiovascular Surgery, Yeungnam University Medical Center, Yeungnam University College of Medicine, Daegu, Republic of Korea;4. Department of Thoracic and Cardiovascular Surgery, Kyungpook National University Hospital, Kyungpook University College of Medicine, Daegu, Republic of Korea;5. Department of Thoracic and Cardiovascular Surgery, Daegu Catholic University Medical Center, Daegu Catholic University College of Medicine, Daegu, Republic of Korea;6. Department of Internal Medicine, Division of Pulmonology, Keimyung University Daegu Dongsan Hospital, Keimyung University College of Medicine, Daegu, Republic of Korea;7. Department of Thoracic and Cardiovascular Surgery, Kyungpook National University Chilgok Hospital, Kyungpook National University College of Medicine, Daegu, Republic of Korea;8. Department of Internal Medicine, Division of Pulmonology, Keimyung University Dongsan Hospital, Keimyung University College of Medicine, Daegu, Republic of Korea |
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| Abstract: | ![]()
BackgroundThe COVID-19 pandemic has caused an epidemic of critical patients, some of whom have been treated with extracorporeal membrane oxygenation (ECMO). This purpose of study is to describe the clinical course of COVID-19 patients treated with ECMO.MethodsA multicentered study of critical patients with COVID-19 treated at six hospitals in Daegu was conducted between January and April 2020.ResultsAmong the 80 patients receiving mechanical ventilation support, 19 (24%) were treated with ECMO included (median age 63.0 years). Eight of the 19 patients (42%) were weaned off ECMO (9.8 days, IQR 7.0-13.7). Among them, four patients were also weaned off mechanical ventilation (33.4 days, IQR 29.3 - 35.7), three were still receiving mechanical ventilation (50.9 days), and one expired after ECMO weaning. According to the univariate analysis, the factor that was associated with successful ECMO weaning was vitamin B12 treatment (p = 0.028).ConclusionsDuring the COVID-19 epidemic, ECMO weaning and mortality rates were 42% and 58%, respectively. |
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