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The use of cerebral computed tomographic angiography as an ancillary investigation to support a clinical diagnosis of death using neurological criteria: a consensus guideline
Authors:E. O. Thomas  A. Manara  R. A. Dineen  A. Mortimer  O. Aziz  P. Dean  P. Elliott  D. M. Summers  P. C. Whitfield  P. J. Hutchinson  D. Gardiner
Affiliation:1. Department of Intensive Care Medicine, University Hospitals NHS Trust Plymouth, UK;2. Department of Intensive Care Medicine, North Bristol NHS Trust, Bristol, UK;3. Faculty of Medicine and Health Sciences, University of Nottingham, UK;4. Department of Radiology, North Bristol NHS Trust, Bristol, UK;5. Bristol Royal Hospital for Children and University Hospital Bristol and Weston NHS Foundation Trust, Bristol, UK;6. Department of Intensive Care Medicine and Anaesthesia, East Lancashire Hospitals NHS Trust, Lancashire, UK;7. Royal College of Anaesthetists, London, UK;8. Department of Neuroradiology, NHS Lothian, Edinburgh, UK;9. South West Neurosurgery Centre, University Hospitals NHS Trust Plymouth, UK;10. Department of Neurosurgery, University of Cambridge, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK;11. Department of Intensive Care Medicine, Nottingham University Hospital NHS Trust, Nottingham, UK
Abstract:This multidisciplinary consensus statement was produced following a recommendation by the Faculty of Intensive Care Medicine to develop a UK guideline for ancillary investigation, when one is required, to support the diagnosis of death using neurological criteria. A multidisciplinary panel reviewed the literature and UK practice in the diagnosis of death using neurological criteria and recommended cerebral CT angiography as the ancillary investigation of choice when death cannot be confirmed by clinical criteria alone. Cerebral CT angiography has been shown to have 100% specificity in supporting a diagnosis of death using neurological criteria and is an investigation available in all acute hospitals in the UK. A standardised technique for performing the investigation is described alongside a reporting template. The panel were unable to make recommendations for ancillary testing in children or patients receiving extracorporeal membrane oxygenation.
Keywords:brain death  brain death testing  CT angiography  diagnosis of death  intensive care medicine
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