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Acupuncture and related therapies for poststroke insomnia: A protocol for systematic review and network meta-analysis
Authors:Chao Zhan  Zhao-Duan Hu  Yan Zhao  Xiao-Ming Fang  Wei Cheng  Song Lu  Zhi-Wei Chen
Affiliation:aHubei University of Chinese Medicine, Wuhan;bHuangshi Traditional Chinese Medicine Hospital, Huangshi, Hubei, China.
Abstract:
Objective:To compare and evaluate the clinical effects on patients with poststroke insomnia of various acupuncture and acupuncture-related therapies.Methods:In order to analyze the direct and indirect evidence from related studies, we used network meta-analysis (NMA). In order to collect randomized controlled trials (RCTs) of acupuncture and related therapies in the treatment of poststroke insomnia, 3 English and 4 Chinese databases were searched. After 2 researchers independently screened the literature, extracted the information, and assessed the probability of bias in the included studies, the data was analyzed using Stata15.0 and WinBUGS1.4.3 software.Results:Based on the existing data, the pros and cons of different acupuncture-related therapies are compared extensively, the effectiveness of different acupuncture-related therapies is ranked compared to drugs with hypnotic effect in poststroke insomnia care, and the best methods or combinations of acupuncture intervention are summarized.Conclusion:This study will provide new evidence for the safety and effectiveness of acupuncture-related therapies in the treatment of poststroke insomnia, and may be helpful for clinicians, poststroke insomnia patients, and clinical guideline makers to choose the optimal combination of acupuncture for the treatment of poststroke insomnia.Registration Number:INPLASY202120028.
Keywords:acupuncture   insomnia severity index (ISI)   network meta-analysis (NMA)   Pittsburgh sleep quality index (PSQI)   poststroke insomnia   self-rating anxiety scale (SAS)   self-rating depression scale (SDS)
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