慈溪市女性乳腺癌危险因素病例对照研究

目的探索慈溪市女性乳腺癌的危险因素。方法选择慈溪市乳腺癌现症病例237例，采用1：1频数匹配的病例对照研究法，进行乳腺癌流行病学调查，并以条件Logistic回归法分析各因素与乳腺癌发生的关系。结果在调整了部分因素的影响后，吃新鲜鲳鱼、吃虾皮（咸干）、常吃西瓜、吃干果、饮用自来水、饮用过滤水、哺乳与乳腺癌的发生呈负相关。而职业为农民、食糖摄入量高、食用霉变食品、常为家庭问题担心、父母恶性肿瘤史、人工流产和口服避孕药与乳腺癌的发生呈正相关。结论进食水果、蔬菜、鱼虾及哺乳为慈溪市女性乳腺癌保护因素；不合理膳食结构、心理因素、遗传、人工流产和口服避孕药为危险因素。

A Case-control Study on Risk Factors of Breast Cancer among Women in Cixi

Objective To explore the risk factors of breast cancer among women in Cixi. Methods A frequency matched case-control study including 237 cases with breast cancer and 237 conavls in Cixi city was carried out. The relatienships between risk factors and breast cancer were analyzed by nen-eonditional logistic regression. Results After adjusting some confounding factors, there were negative correlatiens between breast cancer and taking fresh sea-fish, dry small shrimps, watenrelon, dry fruits, drinking tap water or filtrated tap water frequently as well as breast-feeding respectively. However, being peasant, high intake of sugar, eating food centaminated by fungi, worrying about family problems, family history of malignancy, induced abertien and oral contraceptive intake were positively correlated with breast cancer respectively. Condusion Taking fresh fruits, vegetables, fish and shrimp as well as breast-fecding were the protective factors of breast cancer; correspondingly, urueasonable diet pattern, psychological factors, heredity, induced abortion and oral contraceptive intake would be the risk factors of breast cancer to women.