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儿童口腔正畸治疗的Cochrane系统评价证据
引用本文:张晓歌,杨帆,吴泰相,黄宁,陈扬熙. 儿童口腔正畸治疗的Cochrane系统评价证据[J]. 国际口腔医学杂志, 2009, 36(6): 661-664. DOI: 10.3969/j.issn.1673-5749.2009.06.009
作者姓名:张晓歌  杨帆  吴泰相  黄宁  陈扬熙
作者单位:四川大学华西口腔医院正畸科;四川大学华西医院国家生物治疗重点实验室人类疾病相关多肽研究室;四川大学华西医院中国循证医学中心,四川,成都,610041
摘    要:目的评价目前儿童口腔正畸治疗的Cochrane系统评价证据和纳入系统评价的随机对照试验(RCT)/半随机对照试验(qRCT)的方法学质量。方法检索2008年第4期Cochrane Library数据库中有关儿童口腔正畸治疗的系统评价。结果检索到儿童前牙开胎的正畸和矫形治疗、阻鼾器和功能矫治器治疗儿童阻塞性睡眠呼吸暂停综合征效果、儿童上牙前突正畸治疗和儿童上前牙内倾性深覆胎正畸治疗的4篇系统评价,共纳入12个RCT。依照Cochrane Handbook for Systematic Renewsof Interventions5.0.0版推荐的质量评价方法得出,仅2个RCT为A级,1个RCT为B级,其余9个RCT均为C级。结论Cochrane系统评价是公认的最高质量的研究证据,但目前尚缺少足够强度的RCT证据来支持儿童正畸和矫形治疗疗效的系统评价。建议推行临床试验透明化,实施临床试验注册制度和按照RCT报告的统一标准声明来严格规范RCT的报告。

关 键 词:正畸  系统评价  随机对照试验  方法学

Evidences of Cochrane systematic reviews on orthodontic treatments for children
ZHANG Xiao-ge,YANG Fan,WU Tai-xiang,HUANG Ning,CHEN Yang-xi.. Evidences of Cochrane systematic reviews on orthodontic treatments for children[J]. Journal of International Stomatology, 2009, 36(6): 661-664. DOI: 10.3969/j.issn.1673-5749.2009.06.009
Authors:ZHANG Xiao-ge  YANG Fan  WU Tai-xiang  HUANG Ning  CHEN Yang-xi.
Affiliation:ZHANG Xiao-ge1,YANG Fan2,WU Tai-xiang3,HUANG Ning1,CHEN Yang-xi1.(1. Dept. of Orthodontics,West China College of Stomatology,Sichuan University,Chengdu 610041,China,2. Dept. of Peptides Related with Human Diseases,State Key Laboratory of Biotherapy,West China Hospital,3. Dept. of Chinese Evidence-Based Medicine Center,China)
Abstract:Objective To assess the evidences of Cochrane systematic reviews of orthodontic treatment for children and the methodological quality of all randomized and quasi-randomized controlled trials(RCT/qRCT) of the included systematic reviews. Methods Issue 4, 2008 of the Cochrane Library was searched for systematic reviews on orthodontic treatments for children. All randomized or quasi-randomized controlled trials of Cochrane systematic reviews of orthodontic treatment for children were evaluated. Results Four sy...
Keywords:orthodontics  systematic review  randomized controlled trial  methodology  
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