结直肠癌手术并发症及其影响因素分析

目的：探索结直肠癌患者手术并发症发生情况及其影响因素。方法选取2012年1月至2013年5月间在我院进行手术治疗的结直肠癌患者274例为研究对象，收集他们的临床资料，运用 SPSS 16.0统计软件对数据进行单因素和Logistic回归分析找出对结直肠癌手术并发症有影响的因素。结果结直肠癌患者手术并发症的总发生率为22.23%，肺部感染、伤口感染是最常见的并发症。单因素分析显示内科合并症（P＝0.000）、手术时间（P＝0.022）和Dukes分期（P＝0.012）会影响术后并发症发生。Logistic回归分析显示内科合并症（P＝0.001，OR＝5.213，95%CI 1.124～15.323）和手术时间（P＝0.002，OR＝16.231，95%CI 2.313～16.930）是术后并发症发生的危险因素。结论性别、年龄、烟酒史、肥胖情况、手术方法、麻醉方式、术中失血情况和中转手术并非结直肠癌患者术后并发症的危险因素，而治疗术前内科合并症，缩短手术时间，尽早治疗能够有效地减少术后并发症发生。

Surgical complications and its influence factors of colorectal cancer

Objective To investigate the surgical complications and its influence factors of colorectal cancer patients. Methods Two hundred and seventy-four colorectal cancer patients who were treated in our hospital from January 2012 to May 2013 were chosen as the research objects. Their clinical data were investigated by self-made questionnaire. And the surgical complications and its influence factors of colorectal cancer patients were analyzed by single factor analysis and Logistic regression analysis of SPSS16.0 statistical software in order to find out surgical complications influence factors of colorectal cancer. Results The total incidence of complications in colorectal cancer patients was 22.23%, pulmonary infection, wound infection was the most common complications. Single factor analysis showed that medical comorbidity （P=0.000）, surgery time （P=0.022） and Dukes staging（P=0.012） affected the postoperative complications. Logistic regression analysis showed that medical comorbidity （P=0.001, OR=5.213, 95% CI 1.124-15.323） and operative time（P=0.002, OR=16.231, 95% CI 2.313-16.930） was risk factors of postoperative complications in the colorectal cancer patients. Conclusion Gender, age, history of alcohol and tobacco, obesity, surgical method, anesthesia, intraoperative blood loss and transit operation is not risk factors of postoperative complications in the colorectal cancer patients, but preoperative medical complications, shortening the operation time and early treatment can effectively reduce the postoperative complications.