Inhibition of breast cancer cell invasion by melatonin is mediated through regulation of the p38 mitogen-activated protein kinase signaling pathway |
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| Authors: | Mao Lulu Yuan Lin Slakey Lauren M Jones Frank E Burow Matthew E Hill Steven M |
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| Affiliation: | (1) Department of Structural and Cellular Biology, Tulane University School of Medicine, 1430 Tulane Avenue, New Orleans, LA 70112, USA;(2) Tulane Cancer Center, Tulane University School of Medicine, 1430 Tulane Avenue, New Orleans, LA 70112, USA;(3) Department of Cell and Molecular Biology, Tulane University, 2000 Percival Stern, New Orleans, LA 70118, USA;(4) Department of Medicine, Tulane University School of Medicine, 1430 Tulane Avenue, New Orleans, LA 70112, USA |
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| Abstract: | ![]()
Introduction The pineal gland hormone, melatonin, has been shown by numerous studies to inhibit the proliferation of estrogen receptor α (ERα)-positive breast cancer cell lines. Here, we investigated the role of melatonin in the regulation of breast cancer cell invasion. |
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