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巴曲酶治疗急性脑梗死的临床疗效
引用本文:高爱英. 巴曲酶治疗急性脑梗死的临床疗效[J]. 解放军护理杂志, 2008, 25(20): 7-9
作者姓名:高爱英
作者单位:菏泽市市立医院,神经内科,山东,菏泽,274031
摘    要:
目的探讨巴曲酶静脉溶栓治疗急性脑梗死的临床疗效及安全性。方法将286例急性脑梗死患者随机分为观察组145例和对照组141例,在常规治疗的基础上观察组第1天静脉滴注巴曲酶10BU,第3、5天各5BU静脉滴注;对照组采用低分子右旋糖酐500ml加复方丹参16ml静脉滴注。治疗前后分别进行疗效评定,检测凝血活酶时间(PT)、凝血酶时间(TT)、活化部分凝血酶时间(APTT)、血浆纤维蛋白原(FIB),并于治疗前后5、10d对神经功能缺损进行评分。结果治疗后观察组病例神经功能缺损评分明显低于对照组,差异有统计学意义(P〈0.01);观察组患者的治愈率、显效率、总有效率均明显高于对照组,差异有统计学意义(P〈0.05);治疗12h后,观察组患者的PT、TT、APTT延长,FIB浓度降低,与治疗前比较差异均有统计学意义(P〈0.01)。结论巴曲酶治疗急性脑梗死的疗效显著,安全性好,无明显不良反应。

关 键 词:巴曲酶  急性脑梗死  疗效

Observation on Therapeutic Effects of Batroxobin in Treating Acute Cerebral Infarction
GAO Ai-ying. Observation on Therapeutic Effects of Batroxobin in Treating Acute Cerebral Infarction[J]. Nursing Journal of Chinese People's Liberation Army, 2008, 25(20): 7-9
Authors:GAO Ai-ying
Affiliation:GAO Ai-ying(Neurology Department,Heze Municipal Hospital,Heze 274031,Sh,ong Province,China)
Abstract:
Objective To explore curative effects and safety of intravenous thrombolysis with Batr- oxobin in treating acute cerebral infarction.Methods Two hundreds and eighty-six patients with acute cerebral infarction were randomly divided into observation group(n=145)and control group(n=141).Based on the conventional therapy,Batroxohin was intravenously dripped with 10 Bu on the 1st day and 5 Bu on the 3rd and 5th day.500 ml of low molecular dextran plus 16 ml of compound Danshen was intravenously dripped in the co...
Keywords:batroxobin  acute cerebral infarction  therapeutic effect  
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