Curcumin improves early functional results after experimental spinal cord injury |
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Authors: | Berker Cemil Kivanc Topuz Mehmet Nusret Demircan Gokhan Kurt Kagan Tun Murat Kutlay Osman Ipcioglu Zafer Kucukodaci |
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Affiliation: | (1) Department of Neurosurgery, Faculty of Medicine, Fatih University, 06510, Emek, Ankara, Turkey;(2) Department of Neurosurgery, Haydarpasa Training Hospital, Gulhane Military Medical Academy, Istanbul, Turkey;(3) Department of Neurosurgery, Gazi University, Ankara, Turkey;(4) Department of Neurosurgery, Ankara Numune Education and Research Hospital, Ankara, Turkey;(5) Department of Biochemistry, Haydarpasa Training Hospital, Gulhane Military Medical Academy, Istanbul, Turkey;(6) Department of Pathology, Haydarpasa Training Hospital, Gulhane Military Medical Academy, Istanbul, Turkey |
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Abstract: |
Background Curcumin is a polyphenol extracted from the rhizome of Curcuma longa and well known as a multifunctional drug with anti-oxidative, anticancerous, and anti-inflammatory activities. The aim of the study was to evaluate and compare the effects of the use of the curcumin and the methylprednisolone sodium succinate (MPSS) functionally, biochemically, and pathologically after experimental spinal cord injury (SCI). |
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