| Affiliation: | (1) Crump Institute for Molecular Imaging, Department of Molecular and Medical Pharmacology, The David Geffen School of Medicine at UCLA, Los Angeles, CA, USA;(2) Division of Laboratory Animal Medicine, The David Geffen School of Medicine at UCLA, Los Angeles, CA, USA;(3) Molecular Imaging Program at Stanford (MIPS), Department of Radiology & Bio-X Program, Stanford University, Stanford, CA, USA |
| Abstract: | PurposeThe growing number of mouse and rat experiments, coupled with advances in small-animal imaging systems such as microPET®, optical, microCAT?, microMR, ultrasound and microSPECT, has necessitated a common technical center for imaging small animals.ProceduresAt the UCLA Crump Institute for Molecular Imaging, we have designed and built a facility to support the research interests of a wide range of investigators from multiple disciplines. Requirements to satisfy both research and regulatory oversight have been critically examined. Support is provided for investigator training, study scheduling, data acquisition, archiving, image display, and analysis.ResultsThe center has been in operation for more than 18 months, supporting more than 13,000 individual imaging procedures.ConclusionsWe have created a facility that maximizes our resource utilization while providing optimal investigator support, as well as the means to continually improve the quality and diversity of the science by integrating physical and biological sciences. |
