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Epstein-Barr Virus-associated Smooth Muscle Tumor of the Basal Ganglia in an HIV+ Child: Case Report and Review of the Literature
Authors:Shimareet?Kumar  author-information"  >  author-information__contact u-icon-before"  >  mailto:skumar@cnmc.org"   title="  skumar@cnmc.org"   itemprop="  email"   data-track="  click"   data-track-action="  Email author"   data-track-label="  "  >Email author,Mariarita?Santi,Gilbert?Vezina,Tena?Rosser,Roma S.?Chandra,Robert?Keating
Affiliation:(1) Department of Anatomic Pathology, Suite 1620, Children"rsquo"s National Medical Center, 111 Michigan Avenue N.W., Washington, DC 20010, USA;(2) Department of Radiology, Children"rsquo"s National Medical Center, Washington, DC, USA;(3) Department of Neurology, Children"rsquo"s National Medical Center, Washington, DC, USA;(4) Department of Neurosurgery, Children"rsquo"s National Medical Center, Washington, DC, USA
Abstract:We describe the clinicopathologic features of an Epstein-Barr virus (EBV)-associated smooth muscle tumor arising in the basal ganglia of a 10-year-old human immunodeficiency virus (HIV)-positive child. Only a few cases of intracranial smooth muscle tumors are reported in the literature and virtually all of these have been extra-axial, involving the dura or sinuses in HIV+ adults. Our case underscores the need to include an EBV-associated smooth muscle tumor in the differential diagnosis when evaluating intracranial mass lesions in immunodeficient children.Corresponding author, e-mail:
Keywords:Epstein-Barr virus  human immunodeficiency virus  brain  leiomyoma
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