28例颈内动脉系统急性脑梗塞动脉溶栓治疗

目的分析颈内动脉系统急性脑梗塞动脉溶栓治疗的有效性和安全性。方法对28例颈内动脉急性脑梗塞的患者进行了动脉溶栓治疗．通过造影显示血管再通情况。术后即刻和24h后分别行头颅CT扫描以了解有无颅内出血（ICH）。术后第90天采用Barthel指数（BI）对患者生活状态进行评估。结果28例患者经动脉溶栓治疗，堵塞血管再通18例，部分再通6例，未通4例；症状性颅内出血8例，死亡5例。术后第90天，生活状态优者14例，良者8例，差或者死亡6例。再通患者生活状态明显优于部分再通及未通患者。结论动脉溶栓具有较高的症状性颅内出血率及死亡率。再通患者生活状态较好。

Intra-arterial thrombolysis in 28 patients with acute internal carotid circulation infarction

Objective To evaluate the safety and efficacy of intra-arterial thrombolysis in patients with acute internal carotid circulation infarction.Methods Twenty-eight patients with acute internal carotid circulation infarction were treated with intra-arterial urokinase.Intracerebral hemorrhage(ICH)was investigated immediately and 24 h after the treatment by CT scanning.Barthel Index(BI)was used to evaluate the recovery of neurological functions 90 d after the treatment.Results Of the 28 patients,18 achieved complete recanalization,6 partial recanalization and 4 didn't get any recanalization.ICH was observed in 6 patients.4 patients died.90 d later,14 patients had a good outcome,8 a median outcome and 6 a poor outcome or died.The living status of patients with recanalization was significantly better than that of ones with partial recanalization and non-recanalization.Conclusion The rates of ICH and death following intra-arterial thrombolysis are high.The therapeutic outcome of recanalization is good.