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Disagreement between splenic switch-off and myocardial T1-mapping after caffeine intake
Authors:Dirkjan Kuijpers  Randy van Dijk  Marly van Assen  Theodorus A. M. Kaandorp  Paul R. M. van Dijkman  Rozemarijn Vliegenthart  Pim van der Harst  Matthijs Oudkerk
Affiliation:1.Center for Medical Imaging,University of Groningen, University Medical Center Groningen,Groningen,The Netherlands;2.Department of Cardiology,University of Groningen, University Medical Center Groningen,Groningen,The Netherlands;3.Department of Cardiovascular Imaging HMC-Bronovo,The Hague,The Netherlands;4.Department of Radiology,University of Groningen, University Medical Center Groningen,Groningen,The Netherlands
Abstract:Caffeine is an adenosine receptor antagonist and a possible cause of inadequate stress perfusion. Splenic switch-off (SSO) and splenic rest-stress T1-mapping have been proposed as indicators of stress adequacy during perfusion cardiac magnetic resonance (CMR). We compared myocardial rest-stress T1-mapping with SSO and splenic rest-stress T1-mapping in patients with and without recent coffee intake. We analyzed 344 consecutive patients suspected of myocardial ischemia with adenosine perfusion CMR. All 146 normal CMR studies with a normal T1-rest of the myocardium, used as standard of reference, were included and divided in two groups. 22 patients accidentally ingested coffee
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