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| Elf-1在胃癌组织中的表达及其临床意义 | |
| 引用本文： | 谭雪梅,项锋钢. Elf-1在胃癌组织中的表达及其临床意义[J]. 青岛大学医学院学报, 2008, 44(2): 142-144 |
| 作者姓名： | 谭雪梅 项锋钢 |
| 作者单位： | 青岛大学医学院,学生工作办公室,山东,青岛,266021;青岛大学医学院,附属医院病理科,山东,青岛,266021 |
| 摘 要： | 目的 探讨转录因子Elf-1在胃癌组织中的表达及其与胃癌临床病理学特征的关系.方法 采用免疫组织化学染色的方法检测70例胃癌组织及相应的癌旁组织、远癌黏膜组织中Elf-1的表达,分析Elf-1表达与胃癌及其临床病理特征的关系.结果 Elf-1在胃癌、癌旁组织、远癌黏膜组织中表达的阳性率分别为88.6%、55.7%、5.0%,Elf-1在胃癌中的表达率明显高于癌旁组织及远癌黏膜组织,差异有显著性(Hc=70.11,P<0.01);Elf-1在胃癌中的表达与分化程度、浸润深度、临床分期及淋巴结转移有关(Hc=-4.81～19.62,P<0.01).结论 Elf-1与胃癌的发生及发展有关,检测Elf-1的表达水平对于胃癌早期诊断及预后评估具有重要参考价值. |
| 关 键 词： | Elf-1 癌基因 胃肿瘤 免疫组织化学Ё |
| 文章编号： | 1672-4488(2008)02-0142-03 |
| 修稿时间： | 2008-01-22 |
EXPRESSION OF Elf-1 IN HUMAN GASTRIC CARCINOMA AND ITS CLINICAL SIGNIFICANCE |
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| TAN XUE-MEI,XIANG FENG-GANG. EXPRESSION OF Elf-1 IN HUMAN GASTRIC CARCINOMA AND ITS CLINICAL SIGNIFICANCE[J]. Acta Academiae Medicinae Qingdao Universitatis, 2008, 44(2): 142-144 | |
| Authors: | TAN XUE-MEI XIANG FENG-GANG |
| Affiliation: | TAN XUE-MEI,XIANG FENG-GANG(Department of Students Office,Qingdao University Medical College,Qingdao 266021,China) |
| Abstract: | Objective To investigate the expression of Elf-1 in human gastric carcinoma and its relation to clinical pathology. Methods Elf-1 expressions in cancer tissue and adjacent and distal mucosa,in 70 cases,were investigated by immunohistochemistry.The relationship between the expressions and the pathological characters was analyzed. Results The positive expressions of Elf-1 in the cancer,adjacent tissues and distal mucosa were 88.6%,55.7%,and 5.0%,respectively,the difference between them being significant(Hc=70... |
| Keywords: | Elf-1 Oncogenes Stomach neoplasm Immunohistochemistry |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |