| 基于高通量测序研究半夏泻心汤对3-脱氧葡萄糖醛酮致糖尿病前期大鼠肠道菌群的影响 |
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| 引用本文： | 李杰,杨海梅,宋秀道,周梁,江国荣. 基于高通量测序研究半夏泻心汤对3-脱氧葡萄糖醛酮致糖尿病前期大鼠肠道菌群的影响[J]. 中国临床药理学杂志, 2022, 0(2): 132-136 |
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| 作者姓名： | 李杰 杨海梅 宋秀道 周梁 江国荣 |
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| 作者单位： | 南京中医药大学附属苏州市中医医院中药临床药学实验室;南京中医药大学药学院;苏州市吴门医派研究院中药临床药学实验室 |
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| 基金项目： | 国家自然科学基金资助项目(81973740,82004315)。 |
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| 摘 要： | 目的 研究半夏泻心汤对3-脱氧葡萄糖醛酮(3 DG)致糖尿病前期大鼠肠道菌群的影响.方法 大鼠连续灌胃3DG(50 mg·kg-1·d-1)2周制得糖尿病前期大鼠模型.将雄性SD大鼠随机分为3组:正常组(7只)、模型组(7只)和实验组(3只).造模后,实验组灌胃半夏泻心汤水煎液(5 mL·kg-1),正常组和模型组灌胃...
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| 关 键 词： | 半夏泻心汤 16S rRNA高通量测序 糖尿病前期 肠道菌群 |
Effects of Banxia Xiexintang on gut microbiota in prediabetic rats induced by 3-deoxyglucosone based on high-throughput sequencing |
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| LI Jie,YANG Hai-mei,SONG Xiu-dao,ZHOU Liang,JIANG Guo-rong. Effects of Banxia Xiexintang on gut microbiota in prediabetic rats induced by 3-deoxyglucosone based on high-throughput sequencing[J]. The Chinese Journal of Clinical Pharmacology, 2022, 0(2): 132-136 |
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| Authors: | LI Jie YANG Hai-mei SONG Xiu-dao ZHOU Liang JIANG Guo-rong |
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| Affiliation: | (Clinical Pharmaceutical Laboratory of Traditional Chinese Medicine(TCM),Suzhou TCM Hospital Affiliated to Nanjing University of Chinese Medicine,Suzhou 215009,Jiangsu Province,China;School of Pharmacy,Nanjing University of Chinese Medicine,Nanjing 210023,Jiangsu Province,China;Clinical Pharmaceutical Laboratory of Traditional Chinese Medicine(TCM),Suzhou Academy of Wumen Chinese Medicine,Suzhou 215009,Jiangsu Province,China) |
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| Abstract: | |
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| Keywords: | Banxia Xiexintang high-throughput 16S rRNA gene sequencing prediabetic gut microbiota |
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