CT及PET/CT在诊断胸膜间皮瘤上的应用

目的:分析胸膜间皮瘤的螺旋CT征象特点,并探讨PET/CT对胸膜间皮瘤影像学诊断的辅助补充价值。方法:回顾性分析自1999年2月至2006年6月间经组织细胞学证实的23例胸膜间皮瘤患者螺旋CT及7例患者的PET/CT检查征象。结果:23例胸膜间皮瘤患者中,良性7例,恶性16例。局限性结节样胸膜增厚9例,良性7例,恶性2例;14例弥漫性胸膜增厚均为恶性。应用PET/CT检查的7例患者中,排除手术可行性5例。结论:CT能很好地显示胸膜病变的部位、形态、范围及与周边组织的关系,而PET/CT可更好地鉴别病变的良、恶性,及是否伴有远处转移,对恶性病例的分期更准确,对临床治疗有重要的指导作用。

CT and PET/CT in the diagnosis of pleural mesothelioma

Objective:To study the CT and PET/CT features of pleural mesothelioma and the value of CT and PET/CT imaging in the diagnosis of the disease.Methods:We retrospectively analyzed the spiral CT images of 23 patients and PET/CT images of 7 patients with pleural mesothelioma,all histologically confirmed.Results:Of the 23 cases detected by spiral CT,7 were benign and 16 malignant;local nodular pleural thickening was found in 9 cases,7 benign and 2 malignant;diffuse pleural thickening was observed in 14 cases,all malignant.Of the 7 cases diagnosed by PET/CT,5 were excluded from surgery.Conclusion:CT imaging helps determine the location,shape,extent of the pleural lesion and its relation to the surrounding tissues,while PET/CT is better in the differentiation of pleural mesothelioma and staging of malignancy,and therefore plays an important guiding role in the treatment of the disease.