倍频Q开关掺钕钇铝石榴石激光治疗雀斑疗效观察

目的评估倍频Q开关掺钕钇铝石榴石激光治疗雀斑的疗效。方法总结2004年10月至2007年8月间治疗的47例雀斑患者的资料及治疗后外涂丁卡因凝胶的效果。结果治疗后6个月，47例患者中，治愈38例（80．9％），显效8例（17．0％），有效1例（2．1％），总有效率100％。1年后治愈率为100％。治疗后3个月时有15例（31．9％）出现色素沉着，但于9个月内全部消退。治疗后外涂丁卡因凝胶的起效时间为20～70s，达到最大镇痛效果的时间为2～5min，可以减轻疼痛70％～100％。结论倍频Q开关Nd：YAG激光治疗雀斑有疗效好、不良反应少的优点。但可出现可逆性炎症后色素沉着。治疗后使用丁卡因凝胶，有较好的止痛效果。

Evaluation of frequency-doubled Q-switched Nd: YAG laser in the treatment of freckle

Objective To evaluate the effects of Q-switched Nd: YAG laser in the treatment of freckle. Methods Fourty-seven cases treated by Q-switched Nd: YAG laser between October 2004 to August. 2007 were analyzed. The effects of post-laser treatment of tetracaine gel were evaluated. Results Of 47 cases, 38 were cured (80.9%), 8 were notablely improved (17.0%) and 1 was improved 6 months after treatment. The total efficient rate was 100%. All of them were cured 1 year after treatment. 15 cases had a postinflammatory hyperpigmentation 3 months after the laser treatment which disappeared in 9 months. Furthermore, when the tetracaine gel was used after the laser treatment, the onset time was 20 to 70 seconds, the time of the maxial decreased-pain was 2 to 5 minutes and the maximal decreased-pain was 70%～100%. Conclusions Frequency-doubled Q-switched Nd: YAG laser is an effective tool to treat freckles without any adverse effects. But some of the patients will have a reversible postin-flammatory hyperpigmentation. Tetracaine gel has a rapid and good effects on laser-induced pain when used immedi-ately after laser procedure.