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Isolated central nervous system involvement in adult T-cell lymphoma/leukaemia
Authors:Dungerwalla M  Osuji N  Waldman A D  Al Jehani F  Mehta A  Tailor R  Taylor R  Wotherspoon A  Cogill G  Matutes E
Affiliation:Section of Haemato-Oncology, Royal Marsden NHS Foundation Trust and Institute of Cancer Research, London, UK.
Abstract:
Central nervous system (CNS) presentation of adult T-cell lymphoma/leukaemia is rare, and almost invariably associated with systemic disease. We report an unusual manifestation of adult T-cell lymphoma/leukaemia, with isolated CNS involvement and unusual imaging findings. We also describe objective response to antiviral therapy. To our knowledge, this is the first report of such presentation and response.
Keywords:adult T-cell leukaemia/lymphoma    central nervous system    anti-retrovirals    magnetic resonance imaging
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