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| 牛黄上清微丸的制备工艺 | |
| 引用本文： | 王锦玉,仝燕,王智民,李建荣. 牛黄上清微丸的制备工艺[J]. 中国实验方剂学杂志, 2010, 16(17): 10-12 |
| 作者姓名： | 王锦玉 仝燕 王智民 李建荣 |
| 作者单位： | 中国中医科学院中药研究所,北京,100700 |
| 基金项目： | "重大新药创制"科技重大专项 (2009ZX09301-005) |
| 摘 要： | 目的:建立牛黄上清微丸制备方法。方法:以收率和圆整度优选挤出滚圆法制备工艺。结果:牛黄上清提取物加等量微晶纤维素,混匀,加30%水做黏合剂制软材,选择孔径为1.0 mm的筛板,挤出速度为30 r·min-1,滚圆速度50 Hz,滚圆时间为6 min。结论:微丸外表美观,质量稳定。 |
| 关 键 词： | 牛黄上清微丸 制备工艺 挤出-滚圆法 |
| 收稿时间： | 2010-07-05 |
Preparation Method of Niuhuang Shangqing Pellets |
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| WANG Jin-yu,TONG Yan,WANG Zhi-min and LI Jian-rong. Preparation Method of Niuhuang Shangqing Pellets[J]. China Journal of Experimental Traditional Medical Formulae, 2010, 16(17): 10-12 | |
| Authors: | WANG Jin-yu TONG Yan WANG Zhi-min LI Jian-rong |
| Affiliation: | Institute of Chinese Materia Medica,China Academy of Chinese Medicinal Sciences, BeiJing 100700,China;Institute of Chinese Materia Medica,China Academy of Chinese Medicinal Sciences, BeiJing 100700,China;Institute of Chinese Materia Medica,China Academy of Chinese Medicinal Sciences, BeiJing 100700,China;Institute of Chinese Materia Medica,China Academy of Chinese Medicinal Sciences, BeiJing 100700,China |
| Abstract: | ObJective: To establish a preparation method of Niuhuang Shangqing pellets. Method: Optimization of yield and roundness was prepared by extrusion-spheronization process and researched the dissolution of pellets in vitro. Result: Blend the extraction with MCC, and add adequate water. Squeeze with 30 r ·min-1 and roll 6 min with the rate 50 Hz, drying and screening. Conclusion: The pellets had a good appearance and stable quality. |
| Keywords: | Niuhuang Shangqing pellets preparation extrusion-spheronization |
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